Three high-entropy Sm(Eu,Gd)Cr0.2Mn0.2Fe0.2Co0.2Ni0.2O3 perovskite solid solutions were synthesized using the usual ceramic technology. The XRD investigation at room temperature established a single-phase perovskite product. The Rietveld refinement with the FullProf computer program in the frame of the orthorhombic Pnma (No 62) space group was realized. Along with a decrease in the V unit cell volume from ~224.33 Å3 for the Sm-based sample down to ~221.52 Å3 for the Gd-based sample, an opposite tendency was observed for the unit cell parameters as the ordinal number of the rare-earth cation increased. The average grain size was in the range of 5–8 μm. Field magnetization was measured up to 30 kOe at 50 K and 300 K. The law of approach to saturation was used to determine the Ms spontaneous magnetization that nonlinearly increased from ~1.89 emu/g (Sm) up to ~17.49 emu/g (Gd) and from ~0.59 emu/g (Sm) up to ~3.16 emu/g (Gd) at 50 K and 300 K, respectively. The Mr residual magnetization and Hc coercive force were also determined, while the SQR loop squareness, k magnetic crystallographic anisotropy coefficient, and Ha anisotropy field were calculated. Temperature magnetization was measured in a field of 30 kOe. ZFC and FC magnetization curves were fixed in a field of 100 Oe. It was discovered that the Tmo magnetic ordering temperature downward-curve decreased from ~137.98 K (Sm) down to ~133.99 K (Gd). The spin glass state with ferromagnetic nanoinclusions for all the samples was observed. The <D> average and Dmax maximum diameter of ferromagnetic nanoinclusions were calculated and they were in the range of 40–50 nm and 160–180 nm, respectively. The mechanism of magnetic state formation is discussed in terms of the effects of the A-site cation size and B-site poly-substitution on the indirect superexchange interactions.
The concept of radiation-induced hormesis, whereby a low dose is beneficial and a high dose is detrimental, has been gaining attention in the fields of molecular biology, environmental toxicology and radiation biology. There is a growing body of literature that recognises the importance of hormetic dose response not only in the radiation field, but also with molecular agents. However, there is continuing debate on the magnitude and mechanism of radiation hormetic dose response, which could make further contributions, as a research tool, to science and perhaps eventually to public health due to potential therapeutic benefits for society. The biological phenomena of low dose ionising radiation (LDIR) includes bystander effects, adaptive response, hypersensitivity, radioresistance and genomic instability. In this review, the beneficial and the detrimental effects of LDIR-induced hormesis are explored, together with an overview of its underlying cellular and molecular mechanisms that may potentially provide an insight to the therapeutic implications to human health in the future.
In this paper, a new octagonal close ring resonator (OCRR)-based dumbbell-shaped tuning fork perfect metamaterial absorber for C- and Ku-band applications is presented. This design is a new combination of an octagonal ring close ring resonator with two dumbbell-shaped tuning forks metal strips integrated on epoxy resin dielectric substrate. The proposed perfect metamaterial absorber (PMA) is assessed by finite-integration technique (FIT)-based electromagnetic simulator-Computer simulation technology (CST) software. The anticipated assembly reveals dual resonance frequencies of 6.45 GHz and 14.89 GHz at 99.15% and 99.76% absorption, respectively, for TE incidence. The projected design is augmented through various types of parametric studies, such as design optimization, the effect of the octagonal ring resonator width, and varying the split gap of the double tuning fork. The numerical results are also investigated and verified using the equivalent circuit model, another electromagnetic simulator high frequency structural simulator (HFSS), and different array combinations that showed very negligible disparity. The TE polarization wave is applied to analyze the absorption separately and oblique incidence angle showing polarization insensitivity up to and wide incident angle up to . The presented metamaterial absorber is suitable for satellite communication bands, stealth-coating technology, and defense and security applications.
Spectacular developments in molecular and cellular biology have led to important discoveries in cancer research. Despite cancer is one of the major causes of morbidity and mortality globally, diabetes is one of the most leading sources of group of disorders. Artificial intelligence (AI) has been considered the fourth industrial revolution machine. The most major hurdles in drug discovery and development are the time and expenditures required to sustain the drug research pipeline. Large amounts of data can be explored and generated by AI, which can then be converted into useful knowledge. Because of this, the world’s largest drug companies have already begun to use AI in their drug development research. In the present era, AI has a huge amount of potential for the rapid discovery and development of new anticancer drugs. Clinical studies, electronic medical records, high-resolution medical imaging, and genomic assessments are just a few of the tools that could aid drug development. Large data sets are available to researchers in the pharmaceutical and medical fields, which can be analyzed by advanced AI systems. This review looked at how computational biology and AI technologies may be utilized in cancer precision drug development by combining knowledge of cancer medicines, drug resistance, and structural biology. This review also highlighted a realistic assessment of the potential for AI in understanding and managing diabetes.
Thermoluminescence dosimetry applications range from environmental radiation monitoring to sensing of the doses delivered in radiotherapy, through to verifying the doses of large-scale industrial irradiation. Particular utilisations largely depend upon the sensitivity of the dosimetric medium. In present work the thermoluminescent dosimetric properties of commercial low-cost borosilicate glass slides and glass-fibre filters were characterized, use being made initially of a 250 kV clinical therapy x-beam facility. From this, reproducibility and linearity were determined for radiation doses of 0.5, 1, 2, 4, 6, 8, and 10 Gy. Reproducibility of +/5% was obtained following appropriate screening, excellent linearity to dose also being demonstrated for both the borosilicate glass slides and glass-fibre filters, sufficient to demonstrate the potential of these media for use in radiotherapy dosimetry. Of note is the appreciable but not unsurprising dose response of the nominal 1.0 mm thickness borosilicate glass slides, with a per unit dose response some twice that of the less substantial glass-fibre filters. Further work has characterized the borosilicate glass slides for the megavoltage photons and electrons produced by linacs. A further potential interest results from the boron content, recognizing the associated appreciable neutron cross-sections. It is posited that the additional response observed at 10 MV over that at 6 MV is partly a result of photo-neutron production, a matter that is expected to form the basis of further investigations.
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This study represents the development and analysis of the types of metamaterial structures for terahertz frequency. Recently, investigations about unique coding metamaterial have become well-known among the scientific community since it can manipulate electromagnetic (EM) waves by utilizing various coding sequences. Therefore, several coding and tailored metamaterial designs were compared and numerically analyzed the performances in this research work. The 1-bit coding metamaterial made up of only “0” and “1” elements by adopting two types of unit cells with 0 and π phase responses were analyzed for the coding metamaterial. Moreover, for the numerical simulation analyses, the well-known Computer Simulation Technology (CST) Microwave Studio software was adopted. This investigation focused on the frequency ranges from 0 to 5 THz. On the other hand, the proposed designs were simulated to find their scattering parameter behavior. The comparison of coding and tailored metamaterial revealed slight differences in the RCS values. The coding metamaterial designs manifested RCS values less than −50 dBm2, while tailored metamaterial designs exhibited less than −60 dBm2. Furthermore, the proposed designs displayed various transmission coefficient result curves for both types of metamaterial. Moreover, the bistatic far-field scattering patterns of both metamaterial designs were presented in this work. In a nutshell, the 1-bit coding metamaterial with a unique sequence can influence the EM waves and realize different functionalities.
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