Aloe Vera (AV) is a reputable herbal medical and feed additive. The gel extract of AV contains mucopolysaccharides that stimulate the innate immune response. The reaction to Aloe Vera administration might involve beneficial or drastic responses depending on the dose and extraction method. In the current investigation, two different concentrations of Aloe Vera gel extract at 10% and 20% were orally administrated for one week either alone or as a supplement to yogurt. Wistar albino rats were randomly distributed into6 groups and administered orally : 1 Distilled water (DW) group, 2) Aloe Vera gel extract 10% (AV10) group, 3) Aloe Vera gel extract 20% (AV20) group, 4) Plain yogurt group (Y), 5) Aloe Vera 10% fortified yogurt group (Y + AV10), and 6) Aloe Vera 20% fortified yogurt (Y + AV20) group . The effects of different treatments were investigated on body weight, feed intake, the proliferation of brain astrocytes, differential count of peripheral immune cells, and serum proteins. AV20 neutrophilia with a lymphocytopenia. Glial fibrillary acidic protein (GFAP), a marker of astrocytes, was significantly enhanced in brain tissues that received Aloe Vera-fortified yogurt with nonsignificant enhancement in other groups. No prominent changes were observed in serum proteins and antioxidant activity. In conclusion, Aloe Vera could enhance the proliferation of brain astrocytes and innate peripheral immune cells without further changes in proteins and antioxidant activity and the response of astrocytes to Aloe Vera in the brain is augmented by yogurt.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.