Con los últimos avances en el campo del Big Data, el uso, análisis e interpretación de los datos cobra una especial relevancia en la definición y ajuste de la estrategia de muchas empresas. En este contexto, se identifica la necesidad de introducir en el perfil de los ingenieros y titulados en empresariales, el uso de herramientas de análisis y visualización de datos. Este artículo presenta un caso de diseño de una actividad práctica de sistemas de información basado en aprendizaje experiencial, que combina el uso de un ERP con herramientas de gestión y análisis de datos. La práctica persigue fomentar habilidades ligadas al uso de estas herramientas además de transmitir la importancia de su integración para generar valor en las empresas.
We present a 59-year-old patient with type 2 diabetes mellitus and massive nephrotic syndrome (anasarca) and biochemical syndrome. The renal biopsy showed a membranous nephropathy (MN). In the blood analysis the patient presented antibodies against M-type phospholipase A2 receptor (anti-PLA2R) positive at a very high titer. Given the existence of idiopathic membranous nephropathy (IMN), treatment was started with a modified Ponticelli regimen, with no response, requiring periodic ultrafiltration sessions. Rituximab induces nephrotic syndrome (NS) remission in two-thirds of patients with IMN, even after other treatments have failed. We proposed treatment with rituximab based on published evidence. In IMN, the presence of M-type anti-receptor antibodies of A2 phospholipase is considered highly specific to idiopathic forms, but the presence of such antibodies has not been shown to be associated with a particular clinical profile. Assessing circulating anti-PLA2R autoantibodies and proteinuria may help in monitoring disease activity and guiding personalized rituximab therapy in nephrotic patients with IMN.
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