conditions are associated with mild increase of general inflammatory markers and a further investigation into their relationship shall be investigated.Objective: The aim of this study is to describe the prevalence and incidence of arterial hypertension (AH) recorded in a computerized outpatient information system implemented in almost all primary health centres of Comunidad Valenciana (Spain).Design and Methods: From the information recorded by the primary care (diagnosis of hypertension -ICD 401 to 405 -) and the population assigned to each center is estimated prevalence (total cases diagnosed) and the annual incidence (new cases diagnosed during the year) for the years 2007, 2008 and 2009.We have taken into account for analysis three age groups (under 15 years, between 15 and 64 and over 64) also have analyzed the data by sex.We calculated the confidence interval (95%) to assess whether the differences were statistically significant.
Pomegranate (Punica granatum Linn.) has several medicinal properties. Pomegranate juice has been reported to be an effective source of high amounts of phyto-constituents with many health and nutritional benefits. This work assessed the possible effect on blood pressure (B.P) and heart rate of P. granatum peel ethyl acetate extract (PGE) at a dosage of 400 mg / kg / day on hypertension-induced fludrocortisone Wistar rats. PGE therapy substantially lowered the B.P of hypertensive rats treated with salt fludrocortisones, but the mean blood pressure and heart rate in normotensive rats were not altered. In isolated aortic strip, the contractile reactions to noradrenalin of PGE-treated hypertensive rats have been substantially reduced. The active fraction was purified by successive chromatographic techniques resulted in isolation of quercetin and ursolic acid, this bioactive mixture induced a significant decrease in the blood pressure of hypertensive rats as compared to hypertensive control rats at a concentration of 10 mg/kg.
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