Our results demonstrate significant redox imbalance in cancer patients suggesting their paramount importance in the development of SCCHN.
This was performed to observe various radiological presentations of lung cancer at the initial evaluation and to elicit correlation to histopathological diagnosis in all patients to a tertiary chest care hospital. AIM: To study various radiological presentations among lung cancer patients Method: we included all the patients with lung cancer reviewed during a 12mth period between March 2012 to November 2014 who had a definite tissue diagnosis and whose staging based on CT thorax were available. RESULTS: 65 patients were evaluated. Right sided lesions predominated with 60% and on left side being 40%. On either side put together, upper lobe 46.15% & middle lobe 36.9% and lower lobe 16.9%.Based on location of tumor 26% of the lesions are peripherally located, 24.5% are central localization, 13.8% are located intermedially. Radiological pattern of presentation: 67% of the cases presented as mass lesions, 9% as obstructive pneumonitis and 23% as combined mass with collapse and 23.07% as pleural effusion. Histological pattern of presentation: squamous cell carcinoma is most common type with 49.23%, adeno 33%, small cell 15%, others 1.5% Most of the cases presented to the hospital in stage IV with 56.36% and stage IIIA 16.36% and stage IIIB as 18.18%. CONCLUSION: we observed most of the lung cancers presented as mass lesion with peripherally located tumor and the most common histological type is squamous cell carcinoma, presented at advanced stages.
Granulomatosis with polyangiitis (GPA) is an important form of AAV (ANCA associated vasculitis) syndrome. Being a multisystem disease, it can manifest in several combinations and can mimic an infection or malignancy. CASE PRESENTATION: A 55 years old man presented with cough, expectoration, haemoptysis, chronic otorrhoea and hearing loss. Imaging study suggested malignant mass lesion in right upper lobe with metastasis. HRCT of Temporal bones showed chronic sclerosing mastoiditis with bilateral CSOM. USG Abdomen and urine examination suggested acute glomerulonephritis. Trucut biopsy of lung showed granuloma and ANCA assays showed him C ANCA positive. Treatment with prednisolone and cyclophosphamide resulted in rapid resolution of symptoms and radiological clearance. CONCLUSION: Since GPA can effect almost any organ and a high degree of suspicion should be maintained in any multisystemic disease. Rapid work up with biopsy and ANCA Assay and early treatment with immunosuppressants will prevent irreversible organ damage.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.