Multiple studies have associated post traumatic stress disorder (PTSD) with variable and high rates of smoking documented in different populations. This article will cover the neurobiology behind tobacco use, and its implications in those with PTSD. Discussion on cessation programs (e.g., effectiveness, drug interactions), and controversy over the use of varenicline will also be discussed.
Despite pharmacokinetic and pharmacodynamic evidence, unconventional dosing is seen in clinical practice. This article reviews data in the use of multiple daily dosing of aripiprazole, and agent with a long half-life that is indicated for once daily dosing.
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