Eight new fluoro- and methoxy-substituted benzodiazaborines have been prepared by a simple condensation reaction in high-to-excellent yields. All new compounds have been characterised by several physical methods, including X-ray diffraction studies on three examples. All new compounds were examined for antifungal activities against five species of potentially pathogenic fungi (Aspergillus niger, Aspergillus fumigatus, Rhizoctonia solani, Verticillium albo-atrum, and Verticillium dahliae). While substitution of the aromatic group derived from the 2-formylphenylboronic acid group had an effect on bioactivities, substitution on the parent thioamide C(=S)NH2 group of the starting thiosemicarbazide greatly reduced activities.
The reaction of Cu(II) sulfate or Pd(II) acetate with four salicylaldimines derived from 5-bromosalicylaldehyde and long-chain aliphatic primary amines afforded the corresponding metal complexes 2a-d and 3a-d, respectively. All complexes were characterized by physicochemical and spectroscopic methods. The molecular structure of 2b was determined by a single-crystal X-ray diffraction study. All complexes were tested for their potential antifungal and antibacterial activities.
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