Background: Recently, microwave has shown tremendous research interest and potential for the extraction of phytoconstituents from plant resources as there is a need for the advancement of high performance in the extraction method. Extraction is the first basic step for the preparation of crude extract followed by isolation, characterization of isolated components related to current analytical chemistry. The current use of microwave implements green technology and satisfies the demand of getting the maximum yield of the target compound. Method: Research articles related to the current research topics on Microwave Assisted Extraction (MAE) were collected and reviewed. Results: MAE promises to be a novel extraction technique for the extraction of phytoconstituents from natural sources than other conventional extraction techniques. Conclusion: Microwave assisted extraction is proved to be advantageous as this method permits specificity, higher yield, selectivity, and extraction efficiency over traditional methods such as Soxhlet extraction, maceration and others along with reduced time and solvent consumption, less environmental pollution, and reduced degradation of thermolabile constituents.
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Treatment modalities of various cancers and the delivery strategies of anticancer agents have evolved significantly in the recent past. The severity and fatality of the disease and hurdles to the effective delivery of therapeutic agents have drawn the attention of researchers across the world for proposing novel and effective drug delivery strategies for anticancer therapeutics. Attempts have been made to propose solutions to the diverse limitations like poor pharmacokinetics and higher systemic toxicities of the traditional delivery of anticancer agents. Nanotechnology-based drug delivery systems including lipid-based nanocarriers have demonstrated significant efficiency in this scenario. The review critically assessed the different types of lipid nanocarrier systems for the effective and optimal delivery of anticancer therapeutic agents. The diverse synthesis approaches are discussed for the laboratory scale and commercial development of different categories of lipid nanocarriers. Further, their application in anticancer drug delivery is illustrated in detail followed by a critical appraisal of their safety and toxicity.
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