The present study examined the fear of death among young adults in the wake of the COVID-19. It explored the association between neuroticism and death anxiety during this pandemic crisis, and it also examined the mediating role of perceived stress in this relationship. An online survey of 200 participants, including both students and employed young adults, aged between 18 and 30 years, was conducted. Results showed that neuroticism was positively correlated to death anxiety; however, the relationship was completely mediated by perceived stress. The results and implications are discussed in light of the COVID-19 pandemic.