Lucio’s phenomenon is an uncommon reaction characterized by severe necrotizing
cutaneous lesions that occurs in patients with Lucio’s leprosy and lepromatous
leprosy. It is considered by some authors as a variant of type 2 or 3 reaction.
Death can occur because of blood dyscrasia or sepsis. Precipitating factors
include infections, drugs and pregnancy. We report a 31-year-old female patient
exhibiting both clinical and histopathological features of lepromatous leprosy
and Lucio’s phenomenon presenting favorable response to treatment. We complement
our report with a literature review of the Brazilian cases of Lucio’s phenomenon
published in Portuguese and English.
Angiosarcoma is a rare and aggressive tumor with high rates of metastasis and
relapse. It shows a particular predilection for the skin and superficial soft
tissues. We report three distinct and typical cases of angiosarcoma that were
diagnosed in a single dermatology clinic over the course of less than a year: i)
Angiosarcoma in lower limb affected by chronic lymphedema, featuring
Stewart-Treves syndrome; ii) a case of the most common type of angiosarcoma
loated in the scalp and face of elderly man and; iii) a skin Angiosarcoma in
previously irradiated breast. All lesions presented characteristic
histopathological findings: irregular vascular proliferation that dissects the
collagen bundles with atypical endothelial nuclei projection toward the
lumen.
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