The skin often signals systemic changes. Some neoplastic diseases that affect
internal organs may trigger several cutaneous manifestations. Although these
dermatoses are relatively unusual, the recognition of some typical paraneoplastic
dermatoses may lead to the early diagnosis of a neoplasm and determine a better
prognosis. In this review article, we discuss the paraneoplastic cutaneous
manifestations strongly associated with neoplasms, which include acanthosis nigricans
maligna, tripe palms, erythema gyratum repens, Bazex syndrome, acquired
hypertrichosis lanuginosa, necrolytic migratory erythema, Leser-Trélat sign and
paraneoplastic pemphigus. We also review the clinical manifestations of each
condition and include updated knowledge on disease pathogenesis.
Applicability of scales/indicators for pain monitoring in critically ill patients incapable of verbalizing: a systematic review of the literature Aplicabilidad de escalas/indicadores para el control del dolor en pacientes críticamente incapaces de verbalizar: una revisión sistemática de la literatura
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