The present study aimed to determine the prevalence of Kamino bodies in Reed
nevus, since most studies to date show conflicting data on this issue. This was
a retrospective observational study, in which the histopathology of 19 Reed
nevus lesions were reviewed. The slides were stained by hematoxylin and eosin
and periodic acid-Schiff, with a special focus placed on the identification of
Kamino bodies. Some clinical data were also collected. The median patient age
was 12 years (range of 2 to 58). The women to men ratio was 5:4. Lesions were
located on different parts of the body. Kamino bodies were found in eleven
lesions (57.89%). five showed pigmented Kamino bodies (26.31%), four
non-pigmented Kamino bodies (21,05%), and 2 (10.52%) had both. Kamino bodies,
pigmented or not, are a common histological finding in Reed nevus and may well
represent a good marker to differentiate these from malignant melanomas.
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