Background: Ivermectin is structurally similar to the macrolide antibiotics, but does not have antibacterial activity. It is, however, active against number of ecto-and endoparasites. It has been extensively employed in veterinary medicine, and in humans it is used to treat filarial diseases, principally onchocerciasis. In the year 2016/2017, scabies out break were happened in Ethiopia especially in two zones of Amhara region i.e South Wollo and south Gondar due to illino. Thus, in order to break the infection cycle WHO recommended providing ivermectine as mass drug administration. Objective: To determine the adverse effects of oral Ivermectin in patients who were treated for scabies outbreak in South Gondar, Ethiopia. Patients and Methods: This non randomized, study was conducted in South Gondar, Ethiopia. 90 patients from 90 households and three woredas' were included to the study after the patients were treated for scabies. Results: All patients completed therapy with a certain mild adverse effects of the drug. Moreover, the prevalence of any reported adverse event ranged from 2.9% to 5.8% excluding a persons who weight less than 6killo grams (age less than 2years), non-pregnants and lactating mothers were excluded. Most of the adverse events were appeared on males and children. Mass administrations of ivermectine distributions were well tolerated, relatively effective, handy and easy to use for the patients as well as health professionals. Conclusion: Ivermectin seems to be a safe and effective alternative to other ani-scabietic agents with few and relatively mild adverse effects.
Introduction: Obliterative Arteriopathy of the Lower Limbs (OALL) is one of the most prevalent cardiovascular diseases in the world with high morbidity and economic impact. In Cameroon, this condition is also present but little studied. For this purpose, this study aims to analyze the epidemiological profile and prognosis of patients operated for OALL at the Yaounde General Hospital (YGH). Materials and Methods:We conducted a retrospective longitudinal study in the surgery department of the YGH relating to ninety-seven medical records of OALL operated patients between 2008 and 2018 (ten years) using a quantitative research approach. Results: It emerges from this study that the mean age was 67.1 ± 13.3 years. Male sex was predominant (57.7%). Stroke was the most frequent clinical past history (15.5%). The most frequent cardiovascular risk factors were arterial hypertension (63.9%), diabetes mellitus (41.2%) and smoking (32.9%). Grade III-IV and acute limb ischemia were the most prevalent OALL grades (41.2% and 32% respectively). Amputation was the most practiced surgical procedure (41.2%). The one-year mortality rate was 39.2%. We found no factor associated with one-year survival. Conclusion: We, therefore, suggest that public health actors develop actions and interventions to exercise in order to reduce this health indicator (mortality rate) and revalue the place of psychosocial care in amputees.
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