Changes in phenolic composition and biological activities were investigated in different Limoniastrum monopetalum L. organs. For that, 80% aqueous acetone extracts were used to estimate total phenolic contents and their antioxidant activities were evaluated using DPPHÁ and O 2 Á-radical scavenging activities and reducing power.The efficiency of organ extracts was tested against human pathogen strains. Ultimately, acid hydrolysis of all organs was subjected to RP-HPLC for phenolic identification. Results showed that flower extracts exhibited the highest polyphenol (65.42 GAE/g DW) and flavonoid (35.36 CE/g DW) contents. Stems were enriched in condensed tannin content (21.4 mg CE/g DW) and displayed the best antiradical activities and the highest reducing power. Besides, stem and gall extracts showed the highest efficiency against pathogenic bacteria as compared with those of flower. Concerning the antifungal test, a slight activity was found in gall extracts. The RP-HPLC showed a difference in phenolic compounds that varied as function of organ. In fact, the major phenolic compound varied as function of organ. Results suggest that L. monopetalum could be a promising source of biomolecules for therapeutic and nutraceutical industries and the difference between organs may be related to their physiological role.

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