Background
: Visceral leishmaniasis (VL) type in Syria is Lashmania infantum, a fatal incapacitating disease, which is mostly seen in infants.
Subjects and Methods
: Hospital records of 19 children with VL were retrospectively reviewed. The period of the study was from June 2016 to July 2019.
Results
: The median age of the patients was 45.5 months. None was coinfected with human immunodeficiency virus or known to be immunocompromised. Pallor and anemia were observed in all cases, fever in 13 (68.42%), splenomegaly in 18 (94.7%), hepatomegaly in 11 (57.9%), thrombocytopenia in 15 (78.95%), and leukopenia in nine (47.4%). A bone marrow aspirate was obtained and
Leishmania
amastigotes were detected in all patients. All patients were initially treated with meglumine antimonate; one child did not respond and was treated with lipid formulations of amphotericin B.
Conclusions
: Presentation of VL in the pediatric age group is characterized by pallor, fever, splenomegaly, and hepatomegaly. Hematological and biochemical indices are typical with cytopenias. In all cases, microscopic examination provided a positive diagnosis. Despite recent reports on decreased responses to antimonial drugs of patients with Mediterranean VL, meglumine antimonate treatment appears to be still highly effective in Syria.
Background: Laser in situ keratomileusis (LASIK) is increasingly used worldwide to correct a wide range of refractive errors. Toxic anterior segment syndrome (TASS), a noninfectious inflammatory disease with symptoms and signs that resemble bacterial infection, is a rare complication of LASIK. Case presentation: We report a case of TASS in a 42-year-old male patient after LASIK surgery in both eyes for hyperopia. Diagnosed clinically. Discussion and conclusion: Little information about complications after LASIK is available. TASS is a general term used to describe acute, sterile postoperative anterior segment reactions. Patients with TASS will often experience blurry vision with or without pain within 12 to 48 hours after surgery. Steroids have shown to be effective in resolving the inflammatory response, reducing the pain and recovering the vision.
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