Different anatomical configurations of the sphenoid sinus can seriously affect the access to the sella via the nose. The surgeon should be aware of these findings preoperatively to reach the sella safely and effectively.

Rupture of intracranial dermoid cysts (RICDC) is a rare phenomenon. The mechanism of rupture, pathophysiology of fat in the ventricles and subarachnoid spaces, possible complications, and proper management of such conditions are proposed on the basis of a review of the literature and experience with two cases of ruptured intracranial dermoid cysts (One was in the pineal region, while another was in the fourth ventricle). It is concluded that rupture of intracranial dermoid cysts is usually spontaneous and non-fatal. Persistence of fat in the subarachnoid spaces postoperatively may last asymptomatically for years. Surgery is the only way to deal with these benign lesions. If the capsule is adherent to vital areas, incomplete removal is advised as recurrence and malignant transformation are unlikely to occur.

A distinction between a case report, case series, and descriptive cohorts is absolutely necessary to enable the appropriate indexing, sorting, and application of evidence. Researchers need better training in methods and terminology, and editors and reviewers should scrutinize more carefully manuscripts claiming to be "case series" studies.

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Background Because of the continuing practice variation regarding the extent of glioblastoma (GBM) resection, we sought to systematically examine the recent literature to evaluate the impact of the extent of resection of primary GBM on patients’ survival. Main body of the abstract We examined all the published studies from January 2009 to January 2020 concerning primary glioblastoma resection and survival. The data synthesis was performed using the random-effects model in Review Manager (version 5.3; Cochrane Collaboration). Eight studies met our selection criteria. The included studies involved a total of 2249 patients. A total of 1247 patients underwent gross total resection (GTR) of the GBM, and 1002 experienced an incomplete resection. The mean progression-free survival for GTR versus incomplete resection was 10 versus 6.3 months, and the mean overall survival (GTR vs. incomplete resection) was 28.7 versus 13.5 months. Using the random-effects model, the outcome results revealed that GTR was insignificantly different than incomplete resection on survival among the included cases (P value: 0.47). The quality of evidence of the available studies was of low certainty. Conclusion The outcome results revealed that gross total resection was insignificantly different than incomplete resection on survival among the included cases (P value: 0.47). However, the quality of evidence of the available studies was of low certainty. Additionally, no data on patients’ quality of life were reported across the included studies. Thus, prospective randomized controlled trials are required to investigate both the safety and the survival benefit of GTR of glioblastoma.