Objective The goal of this study was to compare the efficacy of tramadol and paroxetine in the treatment of primary premature ejaculation (PE). Study design This study was a randomized controlled trial performed in the outpatient department of Nishtar Hospital, Multan, from January 2017 to January 2018. Methodology One hundred six patients were diagnosed with PE and included in the study. The patients were categorized into two groups receiving either tramadol or paroxetine through a lottery randomization method. The main variables were baseline PE, baseline satisfaction after intercourse, baseline intravaginal ejaculatory latency time (IELT), ejaculation control, difficulty in ejaculation, and after-treatment satisfaction with sexual intercourse and IELT. We used IBM SPSS Statistics for Windows, Version 23.0 (Armonk, NY: IBM Corp.) for data analysis, and p≤0.05 was considered statistically significant. Results Ejaculation control, difficulty in ejaculation, and distress due to ejaculation in patients in the tramadol group was noted as 24.5%, 7.5%, and 7.5%, respectively. Ejaculation control, difficulty in ejaculation, and distress due to ejaculation in the paroxetine group was noted as 49.1%, 17%, and 24.5%, respectively. The differences were statistically significant within the groups at baseline and after treatment of PE (p<0.001). Conclusion Tramadol is an effective and useful drug as compared to paroxetine for the treatment of PE. Tramadol can be used as an alternative to other medications for the treatment of lifelong PE.
ABSTRACT… Objectives: The aim of this study was to identify the main etiological factors responsible for non-functional kidneys and the most common presenting complaints in patients undergoing simple nephrectomy in a tertiary care hospital. Setting: Urology department of Nishter Medical College and Hospital Multan. Period: January 2014 to June 2015 were selected for this study. Methods: A total of Eighty (80) patients with non-functional kidney, who underwent simple nephrectomy. Patients of any age and gender were included. Patients having non-functional kidney due to any malignancy were excluded from this analysis. Detailed clinical history regarding pain, micturition, radiographic findings and co-morbid conditions was taken from every patients. Results: The mean patient's age was 29.21+11.80 years and the median age was 25 years. Most common presenting complaints was flank pain. Mean Duration of flank pain was 21.86+35.06 months. 45 (56.2%) were presented with Rt. Flank pain, 29 (36.2%) were presented with Lt. Flank pain and 6 (7.5%) were of not having pain. Most common presenting complaint along with flank pain was fever presented in 19 (23.8%) patients. The 2 nd most common was dysuria, 15 (8.8%) patients were presented with flank pain+dysuria. 11 (13.8%) were with flank pain + pyrexia. Stone disease was the most common pathology responsible for non-functional kidney diagnosed in 40 (50%) patients, out of which 35 (43.8%) were with renal stones and 5 (6.2%) with ureteric stones. The 2 nd most common pathology was Uretero-pelvic junction obstruction (UPJO) presented in 25 (31.2%) patients. Conclusion: Renal stones are most common benign cause responsible for most of the nephrectomies and UPJO is the 2 nd most common pathology. While most common presenting complains of patients suffering from non-functional kidney are flank pain, and flank pain along with fever or Pyuria. Key words:Non-functional kidney, flank pain, nephrectomy. Article Citation: Masood N, Hameed A, Javed MI, Zaidi AI, Bilal A, Naeem K. Simple nephrectomy; etiologies and common presentation of non-functional kidneys in patients in a tertiary care hospital.
Objectives: The aim of this study was to identify the main etiological factorsresponsible for non-functional kidneys and the most common presenting complaints in patientsundergoing simple nephrectomy in a tertiary care hospital. Setting: Urology departmentof Nishter Medical College and Hospital Multan. Period: January 2014 to June 2015 wereselected for this study. Methods: A total of Eighty (80) patients with non-functional kidney, whounderwent simple nephrectomy. Patients of any age and gender were included. Patients havingnon-functional kidney due to any malignancy were excluded from this analysis. Detailed clinicalhistory regarding pain, micturition, radiographic findings and co-morbid conditions was takenfrom every patients. Results: The mean patient’s age was 29.21+11.80 years and the medianage was 25 years. Most common presenting complaints was flank pain. Mean Duration of flankpain was 21.86+35.06 months. 45 (56.2%) were presented with Rt. Flank pain, 29 (36.2%) werepresented with Lt. Flank pain and 6 (7.5%) were of not having pain. Most common presentingcomplaint along with flank pain was fever presented in 19 (23.8%) patients. The 2nd mostcommon was dysuria, 15 (8.8%) patients were presented with flank pain+dysuria. 11 (13.8%)were with flank pain + pyrexia. Stone disease was the most common pathology responsible fornon-functional kidney diagnosed in 40 (50%) patients, out of which 35 (43.8%) were with renalstones and 5 (6.2%) with ureteric stones. The 2nd most common pathology was Uretero-pelvicjunction obstruction (UPJO) presented in 25 (31.2%) patients. Conclusion: Renal stones aremost common benign cause responsible for most of the nephrectomies and UPJO is the 2ndmost common pathology. While most common presenting complains of patients suffering fromnon-functional kidney are flank pain, and flank pain along with fever or Pyuria.
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