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Objective: Pancreatic cancer is one of the leading causes of mortality in developed countries and a lethal malignant neoplasm worldwide. This study aims to evaluate the epidemiology of pancreatic cancer incidence and mortality and its relationship with HDI. Methods: This is a descriptive cross-sectional study that is based on cancer incidence data and cancer mortality rates derived from the World Bank for Cancer in 2018. The incidence and mortality rates of Pancreas as well as Pancreas cancer distribution maps were derived for world countries. The data analysis was conducted using correlation test, and regression tests were used to evaluate the correlation of the incidence and mortality of Pancreas with HDI. The statistical analysis was carried out by Stata-14, and a significance level of 0.05 was considered. Results: The highest incidence of pancreatic cancer was reported in Asia with 214499 (46.7%) cases and the lowest incidence was related to Oceania with 4529 cases (99.9%). The results showed a positive and significant correlation between incidence (R = 0.764, P <0.0001) and mortality (R = 0.0.771, P <0.0001) of pancreatic cancer and the HDI index. The results of ANOVA revealed that the highest mean incidence was related to the very high HDI (P <0.0001) and the highest mortality was connected to the very high human development (P <0.0001). The results exhibited that incidence was positively and significantly correlated with GNI (r = 0.497, P <0.0001), MYS (r = 0.746, P <0.0001), LEB (r = 0.676, <0.0001) and EYS (r = 0.738, P <0.0001). Also, a significant positive correlation was found between mortality and GNI (r = 0.507, P <0.0001), MYS (r = 0.745, P <0.0001), LEB (r = 0.679, <0.0001), and EYS (r = 0.748, P <0.0001). Conclusion: Given the higher incidence and mortality of pancreatic cancer in countries with HDI, it is necessary to pay a greater attention to risk factors and appropriate planning to reduce these factors and minimize the impact and mortality rate of this disease.

BackgroundQuality of life in patients affected with chronic diseases has developed into a therapeutic objective as the best tool to evaluate response to treatment and medical care. The purpose of this study was to evaluate quality of life and its related factors in tuberculosis patients receiving directly observed treatment short-course in Iran.MethodsThis was a cross-sectional research with a descriptive-analytic design. Sample size included 71 patients affected with tuberculosis based on census method; so that, at the time of the study, all the tuberculosis patients were recruited in this research. The data collection instrument was a questionnaire comprised of two parts including demographic characteristics information and standard 36-Item Short Form Health Survey (SF-36). The data were also analyzed using SPSS Statistics along with descriptive and analytic statistics and independent t-tests, analysis of variance (ANOVA), and Chi-square test.ResultsThe lowest mean score was 63.58 ± 10.16 and 62.82 ± 15.2 related to limited physical activity following mental problems and social functioning, respectively. Furthermore, the findings of the independent t-test demonstrated that the mean scores of quality of life among men and women, those with pulmonic and non-pulmonic tuberculosis, patient's place of residence and the stage of treatment were statistically and significantly different.ConclusionAccording to the above results, tuberculosis and its treatment have impact on the social function, mental, and emotional aspects of the quality of life of patients, Attention to and monitoring of the quality of life as a follow up of the treatment and care intervention in these patients is necessary.

Aromatherapy (Lavender essential oil) significantly reduced fatigue in patients with knee osteoarthritis. Thus, due to the high prevalence of knee osteoarthritis, this method is recommended to patents with osteoarthritis because of its availability, security, and cost-effectiveness.

Background:Ejection fraction promotion in heart failure patients reduces mortalities and limitations.Objectives:This study was to investigate the effect of exercise on ejection fraction of chronic heart failure patients.Patients and Methods:The present study was conducted on patients with chronic heart failure. 66 patients were divided randomly into two experimental and control groups of 33 each. The subjects were male and female. The patients in experimental group followed an exercise program three sessions per week for 24 weeks. Echocardiography and quality of life questionnaire were used to gather data. The data were analyzed by SPSS 18 through pair and independent t-test.Results:The results indicated a significant difference in left ventricular diameter (LV-ESD, LV-EDD) and ejection fraction at the end of exercise program in experimental group and 24 weeks after in control group. There was a significant difference in quality of life in physical performance, activity limitation following physical problems, energy and fatigue, social performance, physical pain, and public health (P < 0.05 for all) between two groups.Conclusions:Exercise program increases ejection fraction and quality of life in chronic heart failure patients, associated with management of disease by health team.