Migraine is a recurrent headache syndrome with a wide spectrum of symptoms. The diagnosis of migraine is mostly made retrospectively, taking into account the characteristics of the headache and other symptoms. It is not known enough how migraine headache starts and in which brain regions it occurs. It is known that changes in the excitability of brainstem nuclei affect endogenous pain mechanisms and unilateral involvement of trigeminovascular structures are effective mechanisms in migraine development. Understanding the role of the cerebellum in migraine disease is a fairly new topic in neuroscience. 19 Mıgraıne Patıents (MP) and 14 Healthy Controllers (HC) partıcıpated ın our study. For the volumetric analysis of the cerebellum, the ceres method of volbrain, which is an automatic brain volume calculation method, was used and the volumes of the cerebellum structures were obtained. SPSS 22.0 program was used for the analysis of the data and the level of significance was accepted as p
Introduction: Essential tremor (ET) and Parkinson's disease (PD) are the two most commonly encountered tremor disorders in movement disorders. Diffusion tensor imaging (DTI) is one of the best in vivo ways of mapping white matter pathways in the human brain. The aim of our study was to investigate diffusion variables and cerebellum volume in ET and PD using parcellation methods. Methods: Our study included 20 ET, 20 PD and 20 healthy controls. Fraction Anisotropy (FA) and Mean Diffusivity (MD) values were obtained with DTI, while the volume of each lobe of the cerebellum was obtained with T1 images. One-way ANOVA was used for intergroup analysis and Scheffe test was used for post-hoc analysis. Results: Significant differences were found in the diffusion values of the pedunculus cerebellaris, fornix stria, superior longitudinal fasciculus, sagittal stratum, cerebral pedunculus, tapatum and thalamus of ET and PD. Lobule V, Lobule IX, Lobule X volumes of the cerebellum showed significant differences between the groups. Conclusion: Stria thermialis shows involvement of mesolimbic dopaminergic system in PD and it is thought that disruption of strial networks leads to changes in the activity of cerebellar networks and reveals the role of the cerebellum in tremor. It is obvious that cerebellar thalamocortical pathways are affected in Parkinson's disease. In Parkinson's disease, patients should be evaluated for visual processing, conceptualisation, postural instability and gait disturbance to clarify the diagnosis or to differentiate from essential tremor.
Backgrounds: Erector spinae plane block (ESPB) has become very popular for post-operative and chronic pain management. It is aimed to observe the contrast agent distributions of three different methods anatomically and radiologically in ultrasound-guided sacral ESPB interventions.Materials and Methods: Six cadavers were enrolled and they were grouped into three groups; median, intermediate, and lateral approaches. An ultrasound-guided ESPB was performed with a mixture of radio-opaque and dye. After 30 minutes, the distribution of the solution was observed in the cadavers by computed tomography (CT) examination. Totally after 60 minutes of intervention, the median and intermediate groups of cadavers were dissected in order to observe the dye spread in the median group and the intermediate group. The lateral group dissection wasn’t performed according to radiologic findings.Results: CT images presented a pooling of the radio-opaque at subcutaneous tissue in the median group, at erector spinae in the intermediate group, and at gluteus maximus in the lateral group of cadavers. In addition to compartment spreads, images presented anterior transition of the contrast agent at only median group cadavers. Dissection findings presented pooling of the methylene blue at subcutaneous tissue between S1 and S5 horizontal planes at the median group. The red acrylic paint spread was detected between L2-S3 levels in the erector spinae muscle group.Conclusion: Radiocontrast dye was detected at superficial, erector spinae, and gluteus maximus compartments respectively at median, intermediate, and lateral cadaver groups both radiological and anatomically. Anterior transition of the radiocontrast was detected in only the median cadaver group.
Backgrounds: Erector spinae plane block (ESPB) has become very popular for post-operative and chronic pain management. ESPB applications sacral area procedures have been named 'sacral ESPB’. This study is aimed to conduct a cadaveric study to determine how local anesthesia was distributed at median and intermediate approaches of the sacral region ESPB procedures. Materials and Methods: Four cadavers were grouped into two groups; median and intermediate approaches. An ultrasound-guided ESPB was performed with a mixture of radiocontrast and dye. After the distribution of the solution was observed by computed tomography, cadavers were dissected in order to observe the dye spread in the groups. Results: CT Images of the median group demonstrated subcutaneous pooling of contrast agents between S1 and S5 horizontal planes. Contrast agent passing from the sacral foramina to the anterior of the sacrum via spinal nerves was also observed between S2-S5. In the intermediate group contrast distribution was observed along the bilateral erector spinae muscle between L2-S3 horizontal planes, and no anterior transition was detected. Dissection findings in the median group, methylene blue spread was observed in the subcutaneous tissue area between the S1-S5 horizontal planes. There was no methylene blue solution spread under the superficial fascia or the muscle plane. In the intermediate group, the red-colored radiocontrast solution was detected between the L2-S3 intervertebral levels in the erector spinae muscle group. Conclusion: Radiocontrast dye was detected at superficial and erector spinae compartments respectively at median and intermediate cadaver groups both radiological and anatomically. The anterior transition of the radiocontrast was detected in only the median cadaver group. Clinical Trial: Karadeniz Technical University Ethics Approval No: 2022/229, ClinicalTrials.gov ID: NCT05716061
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.