Background This was a hospital registry-based retrospective age-matched cohort study that aimed to compare pregnancy and neonatal outcomes of women with pre-existing mental disorders with those of mentally healthy women. Methods A matched cohort retrospective study was carried out in the Department of Obstetrics and Gynecology, Hospital of Lithuanian University of Health Sciences Kauno Klinikos, a tertiary health care institution. Medical records of pregnant women who gave birth from 2006 to 2015 were used. The study group was comprised of 131 pregnant women with mental disorders matched to 228 mentally healthy controls. The primary outcomes assessed were antenatal care characteristics; secondary outcomes were neonatal complications. Results Pregnant women with pre-existing mental health disorders were significantly more likely to have low education, be unmarried and unemployed, have a disability that led to lower working capacity, smoke more frequently, have chronic concomitant diseases, attend fewer antenatal visits, gain less weight, be hospitalized during pregnancy, spend more time in hospital during the postpartum period, and were less likely to breastfeed their newborns. The newborns of women with pre-existing mental disorders were small for gestational age (SGA) more often than those of healthy controls (12.9% vs. 7.6%, p < 0.05). No difference was found comparing the methods of delivery. Conclusions Women with pre-existing mental health disorders had a worse course of pregnancy. Mental illness increased the risk to deliver a SGA newborn (RR 2.055, 95% CI 1.081–3.908).
Participants: Fifty-two prepubertal girls aged 1-9 years diagnosed with vulvovaginitis, and 42 age-matched healthy controls. Interventions and Main Outcome Measures: Samples for microbiological culture were collected using sterile cotton swabs from the introitus and the lower third of the vagina from all study participants. Microbiological findings were analyzed according to bacteria type and intensity of growth. Results: Most of the vaginal microbiological swab results were positive for bacterial growth: 47 (90.4%) and 34 (80.9%) were similar in the study and control groups, respectively (P 5 .24). Sixteen (30.8%) and 9 (21.4%) of the microbiological traits results in the case and control groups, respectively, were regarded as potential causative agents (P 5 .27). Streptococcus pyogenes was the most frequent pathogen in the study group (P 5 .03); all other microorganisms detected as either a pure or dominant growth in the control group, were considered opportunistic. Conclusions: Vaginal bacterial culture results were positive in prepubertal girls with vulvovaginitis and in healthy controls. Nonspecific vulvovaginitis without a dominant/isolated pathogen was seen to be more common than vulvovaginitis with a potential causative agent. Clinical symptoms were more frequent among girls when the potential infectious agent was identified.
One of the main challenges of contemporary psychiatry in treating patients with schizophrenia is the early diagnostics and timely prevention of relapse of this disorder. Objective: The goal of the study was to find the potential causes of psychotic episode recurrence and its first symptoms in rehospitalized patients with schizophrenia. Methods: Patients with schizophrenia, who were urgently hospitalized to KUM Psychiatry clinic and had less than three psychotic episodes, took part in the study (N=97). Medical documentation and a structured questionnaire, designed by the authors, were used to evaluate anamnesis data. Results: The main causes of relapse were: willful discontinuation of psychopharmacotherapy (50% of the cases), spontaneous relapses without any clear exogenous cause (20%), and onetime alcohol intoxication (8%). The patients and their family members indicated the following first symptoms of relapse: anxiety, fear (73%), sleep disorders (62%), aggression (52%), delusions and/ or hallucinations (37%). The symptoms tended to occur in combinations rather than individually. Conclusions: Causes and symptoms of schizophrenia relapse differ from patient to patient. It is possible to prevent the relapse knowing the common causes and first symptoms, because most of the patients are able to detect the first symptoms themselves.
Objective:Suicidal behavior becomes more and more actual problem in many countries. Lithuania is known as a country where suicides rate, especially among young people, is the highest in Europe.The goal of this research was to establish the coherence between family, psychosocial characteristics and teenagers' suicide behavior.Methods:Two groups of teenagers from 14 to 17 were researched: the analyzed group (N=109) and the control group (N=218). To evaluate anamnesis, psychosocial factors of the researched teenagers, structural questionnaire, concluded by the authors was presented.Seeking to establish the coherence between psychosocial factors and suicide behavior, the comparisons were made between the frequencies of this factor among 14 – 17 year old teenagers, having no suicide anamnesis and the teenagers who have tried to commit a suicide.Results:The data analysis proved the statistically reliable evidence that in analyzed group both male and female teenagers, who have tried to commit a suicide, live in not full families (p<0,001). The frequent behavior in such families is addiction of both or one of the parents to alcohol (p<0,001); physical punishment is not an exception (p<0,001). The teenagers who have tried to commit a suicide indicated that they more often than the teenagers in the control group fell badly or even very badly among their contemporaries (p<0,001) and most of their time they spend alone (p<0,001).Conclusions:According to the results, the psychosocial factors and teenagers suicidal behavior are related, but only they themself can't predeterminate the suicide.
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