No abstract

(OR 2.1, p < 0.001); 81.4% in GU (OR 1.8, p < 0.001 ); 79.9% in erosive gastropathy (OR 1.4, p = 0.03) and 77.4% in erosive esophagitis (OR 1.1, p = NS) (Rev Med Chile 2010; 138: 529-535).

endoscopic submucosal dissection for early gastric cancer introduction: Endoscopic submucosal dissection (ESD) is nowadays the standard treatment for a subgroup of early gastric cancer with low risk of lymph node metastasis. This procedure has the advantage of achieving a higher percentage of negative margins and of allowing resections of larger tumors compared with the endoscopic mucosal resection (EMR) method, being less invasive compared with surgery. aim: To analyze the postoperative outcomes, histology and overall survival of patients undergoing ESD in our center. methods: Descriptive study. Data were collected from clinical records of patients undergoing ESD from January 2008 to June 2012. results: 15 patients (8 males and 7 females, median age 70 years (45-88)) were included. The tumor was located at upper, middle and lower third in 2, 5 and 8 patients, respectively. Median tumor size was 13.5 mm (6-21). Most tumors were classified as type IIc. Among postoperative complications, there was 1 gastric bleeding and 3 gastric perforations. Hospital stay was 3 days (1-23). There was no mortality. There was one case of submucosal invasion. negative margins were achieved in 86.7%. There was one deep and one lateral positive margin, managed by surgery and re-ESD, respectively. At 16 months (7-61) of median follow-up, overall survival was 100%. Tumor recurrence was observed in one patient at 51 months, was treated by surgery. conclusion: ESD is a feasible technique in the minimally invasive management of early gastric cancer, allowing a high percentage of negative margins.