Glomerular filtration rate (GFR) was studied by measuring the 51-Cr-EDTA clearance with single bolus injection technique in 107 men exposed to styrene, toluene or toluene and xylene in their professions and in 48 non-exposed male controls. The clearance values of the controls were significantly related both to body surface area (BSA) and age. These relations were used to calculate expected clearances for the exposed subjects. The clearances of the exposed subjects were on an average 3.8% higher than expected, according to BSA and age in this group. This divergence was not significant. Thus, no reduction in GFR was found in the subjects exposed to organic solvents.
4 (1978) 179-183. Photofluorography was performed on 1,542 male construction workers in the Stockholm area. Postero-anterior, lateral and two anterior oblique views were obtained. The pleural and pulmonary changes found were classif~ed into six groups. The results were correlated to the subjects' calculated weight index and to the occupational history of asbestos exposure and previous lung or pleural disease. There was a strong positive assoc1ation between a high weight index and changes interpreted as increased amount of extrapleural fat. There was also a positive association between irregular pLeural thickenings and adhesions located mainly around the base of the lung and a clinical history of pleural or pulmonary disease. The importance of taking other etiological :flactors than exposure to asbestos dust into consideration is emphasized when pleural changes are detected in apparently healthy people.
ABSTRACT. Glomerular filtration rate (GFR) was studied by measuring the 51‐Cr‐EDTA clearance with single bolus injection technique in 107 men exposed to styrene, toluene or toluene and xylene in their professions and in 48 non‐exposed male controls. The clearance values of the controls were significantly related both to body surface area (BSA) and age. These relations were used to calculate expected clearances for the exposed subjects. The clearances of the exposed subjects were on an average 3.8% higher than expected, according to BSA and age in this group. This divergence was not significant. Thus, no reduction in GFR was found in the subjects exposed to organic solvents.
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