The past 40 years have witnessed extensive research on fractal structure and scale-free dynamics in the brain. Although considerable progress has been made, a comprehensive picture has yet to emerge, and needs further linking to a mechanistic account of brain function. Here, we review these concepts, connecting observations across different levels of organization, from both a structural and functional perspective. We argue that, paradoxically, the level of cortical circuits is the least understood from a structural point of view and perhaps the best studied from a dynamical one. We further link observations about scale-freeness and fractality with evidence that the environment provides constraints that may explain the usefulness of fractal structure and scale-free dynamics in the brain. Moreover, we discuss evidence that behavior exhibits scale-free properties, likely emerging from similarly organized brain dynamics, enabling an organism to thrive in an environment that shares the same organizational principles. Finally, we review the sparse evidence for and try to speculate on the functional consequences of fractality and scale-freeness for brain computation. These properties may endow the brain with computational capabilities that transcend current models of neural computation and could hold the key to unraveling how the brain constructs percepts and generates behavior.

The question whether the Simplex method admits a polynomial time pivot rule remains one of the most important open questions in discrete optimization. Zadeh's pivot rule had long been a promising candidate, before Friedmann (IPCO, 2011) presented a subexponential instance, based on a close relation to policy iteration algorithms for Markov decision processes (MDPs). We investigate Friedmann's lower bound example and exhibit three flaws in the corresponding MDP: We show that (a) the initial policy for the policy iteration does not produce the required occurrence records and improving switches, (b) the specification of occurrence records is not entirely accurate, and (c) the sequence of improving switches used by Friedmann does not consistently follow Zadeh's pivot rule. In this paper, we resolve each of these issues by adapting Friedmann's construction. While the first two issues require only minor changes to the specifications of the initial policy and the occurrence records, the third issue requires a significantly more sophisticated ordering and associated tie-breaking rule that are in accordance with the LEAST-ENTERED pivot rule. Most importantly, our changes do not affect the macroscopic structure of Friedmann's MDP, and thus we are able to retain his original result.

A variety of behaviors like spatial navigation or bodily motion can be formulated as graph traversal problems through cognitive maps. We present a neural network model which can solve such tasks and is compatible with a broad range of empirical findings about the mammalian neocortex and hippocampus. The neurons and synaptic connections in the model represent structures that can result from self-organization into a cognitive map via Hebbian learning, i.e. into a graph in which each neuron represents a point of some abstract task-relevant manifold and the recurrent connections encode a distance metric on the manifold. Graph traversal problems are solved by wave-like activation patterns which travel through the recurrent network and guide a localized peak of activity onto a path from some starting position to a target state.

The question whether the Simplex Algorithm admits an efficient pivot rule remains one of the most important open questions in discrete optimization. While many natural, deterministic pivot rules are known to yield exponential running times, the random-facet rule was shown to have a subexponential running time. For a long time, Zadeh’s rule remained the most prominent candidate for the first deterministic pivot rule with subexponential running time. We present a lower bound construction that shows that Zadeh’s rule is in fact exponential in the worst case. Our construction is based on a close relation to the Strategy Improvement Algorithm for Parity Games and the Policy Iteration Algorithm for Markov Decision Processes, and we also obtain exponential lower bounds for Zadeh’s rule in these contexts.