<b><i>Introduction:</i></b> While vitamin deficiency after bariatric surgery has been repeatedly described, few studies have focused on adequate micronutrient status. In this study, we examine the prevalence of vitamin and micronutrient deficiency for the first 3 years after surgery. <b><i>Methods:</i></b> Out of 1,216 patients undergoing surgery, 485 who underwent postoperative follow-up in an outpatient clinic between 2010 and 2019 were included in this evaluation (76.9% women, mean age 42 ± 12 years, mean BMI: year 1, 33.9 ± 19.2; year 2, 29.7 ± 8.7; year 3, 26.2 ± 4.0). Weight and cardiovascular risk factors as well as ferritin, vitamin B12, folic acid, 25-OH-vitamin D, vitamin A, vitamin E, zinc, copper, and selenium were evaluated. Deficits were defined as follows: ferritin &#x3c;15 µg/L, vitamin B12 &#x3c;197 pg/mL, folic acid &#x3c;4.4 ng/mL, 25-OH-vitamin D &#x3c;75 nmol/L, vitamin A &#x3c;1.05 µmol/L, vitamin E &#x3c;12 µmol/L, zinc &#x3c;0.54 mg/L, copper &#x3c;0.81 mg/L, and selenium &#x3c;50 µg/L. All patients underwent dietary counselling and substitution of the respective deficits as appropriate. <b><i>Results:</i></b> One year after bariatric surgery, 485 patients completed follow-up. This number decreased to 114 patients in year 2, and 80 patients in year 3. Overall, 42.7% (<i>n</i> = 207) underwent sleeve gastrectomy, 43.7% (<i>n</i> = 211) Roux-en-Y-gastric bypass, and 13.9% (<i>n</i> = 67) gastric banding. The following deficits were found (year 1/2/3): ferritin, 21.6/35.0/32.5%; vitamin B12, 14.3/1.8/6.3%; folic acid, 29.7/21.6/15.3%; 25-OH-vitamin D, 70.8/67.0/57.4%; vitamin A, 13.2/8.9/12.8%; vitamin E, 0%; zinc, 1.7/0/1.5%; copper, 10.4/12.2/11.9%; selenium, 11.1/4.3/0%. <b><i>Conclusion:</i></b> As seen in other studies, the follow-up frequency decreased over the years. Despite intensive substitution, the extent of some deficiencies increased or did not improve. These results suggest reinforcing measures to motivate patients for regular follow-up visits, considering closer monitoring schedules, and improving supplementation strategies.

Background: Aortic root ectasia might induce hemostatic disorders in patients with Marfan syndrome (MFS) via altered blood flow and rheology. The aim of this study was to explore the hemostasis in patients with MFS compared with healthy controls.Methods: In this cross-sectional case-control study we included patients with verified MFS (n=51) and sexand age-matched healthy controls (n=50). Main criteria were the aortic root in echocardiography and cardiac magnetic resonance imaging (MRI), and the coagulation status.Results: When compared with healthy controls, patients with MFS showed significantly increased diameters of the aortic roots (43.0±7.72 vs. 28.8±3.74 mm, P<0.001) and aortic Z-scores (4.36±2.77 vs. 0.948±1.09, P<0.001), considerably higher values of Multiplate ® tests (e.g., MP-ADP: 878.4±201.7 vs.

No abstract

No abstract