Multi-energy CT takes advantage of the non-linearly varying attenuation properties of elemental media with respect to energy, enabling more precise material identification than single-energy CT. The increased precision comes with the cost of a higher radiation dose. A straightforward way to lower the dose is to reduce the number of projections per energy, but this makes tomographic reconstruction more ill-posed. In this paper, we propose how this problem can be overcome with a combination of a regularization method that promotes structural similarity between images at different energies and a suitably selected low-dose data acquisition protocol using non-overlapping projections. The performance of various joint regularization models is assessed with both simulated and experimental data, using the novel low-dose data acquisition protocol. Three of the models are well-established, namely the joint total variation, the linear parallel level sets and the spectral smoothness promoting regularization models. Furthermore, one new joint regularization model is introduced for multi-energy CT: a regularization based on the structure function from the structural similarity index. The findings show that joint regularization outperforms individual channel-by-channel reconstruction. Furthermore, the proposed combination of joint reconstruction and non-overlapping projection geometry enables significant reduction of radiation dose.
Background The high requirements for mammography image quality necessitate a systematic quality assurance process. Digital imaging allows automation of the image quality analysis, which can potentially improve repeatability and objectivity compared to a visual evaluation made by the users. Purpose To develop an automatic image quality analysis software for daily mammography quality control in a multi-unit imaging center. Material and Methods An automated image quality analysis software using the discrete wavelet transform and multiresolution analysis was developed for the American College of Radiology accreditation phantom. The software was validated by analyzing 60 randomly selected phantom images from six mammography systems and 20 phantom images with different dose levels from one mammography system. The results were compared to a visual analysis made by four reviewers. Additionally, long-term image quality trends of a full-field digital mammography system and a computed radiography mammography system were investigated. Results The automated software produced feature detection levels comparable to visual analysis. The agreement was good in the case of fibers, while the software detected somewhat more microcalcifications and characteristic masses. Long-term follow-up via a quality assurance web portal demonstrated the feasibility of using the software for monitoring the performance of mammography systems in a multi-unit imaging center. Conclusion Automated image quality analysis enables monitoring the performance of digital mammography systems in an efficient, centralized manner.
This work considers synergistic multi-spectral CT reconstruction where information from all available energy channels is combined to improve the reconstruction of each individual channel. We propose to fuse these available data (represented by a single sinogram) to obtain a polyenergetic image which keeps structural information shared by the energy channels with increased signal-to-noise ratio. This new image is used as prior information during a channel-by-channel minimization process through the directional total variation. We analyse the use of directional total variation within variational regularization and iterative regularization. Our numerical results on simulated and experimental data show improvements in terms of image quality and in computational speed. This article is part of the theme issue ‘Synergistic tomographic image reconstruction: part 2’.
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