Immunotherapy has considerably improved clinical outcomes in different types of cancers but has also been associated with the development of myocarditis, especially with that mediated by immune checkpoint inhibitors. To the best of our knowledge, these are the first cases of myocarditis after anti‐GD2 immunotherapy reported to date. We present two cases of paediatric patients who, after anti‐GD2 infusion, presented severe myocarditis with myocardial hypertrophy detected on echocardiography and confirmed with cardiac magnetic resonance imaging. An increase in myocardial T1 and extracellular volume of up to 30% was observed with heterogeneous intramyocardial late enhancement. Myocarditis after anti‐GD2 immunotherapy may be more common than appreciated, occurs early after starting treatment, has a malignant course, and responds to higher steroid doses.
Presentamos dos casos clínicos de sendos niños con diagnóstico inicial de comunicación interventricular (CIV) con estenosis de tipo subpulmonar. La ecocardiografía inicial mostraba una posible CIV con algunas peculiaridades que precisaron más estudios de imagen. Estos estudios fueron la clave para el diagnóstico diferencial de una formación sacular en el septo basal por debajo de la válvula aórtica y que incluyó el divertículo o una cámara accesoria del ventrículo izquierdo. Ambos pacientes fueron intervenidos. Los hallazgos operatorios confirmaron el diagnóstico de divertículo de ventrículo izquierdo
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