We describe a catalytic system composed of rhodium nanoparticles immobilized in a Lewis acidic ionic liquid. The combined system catalyzes the hydrogenation of quinolines, pyridines, benzofurans, and furan to access the corresponding heterocycles, important molecules present in fine chemicals, agrochemicals, and pharmaceuticals. The catalyst is highly selective, acting only on the heteroaromatic ring, and not interfering with other reducible functional groups.
We describe a catalytic system composed of rhodium nanoparticles immobilized in a Lewis acidic ionic liquid. The combined system catalyzes the hydrogenation of quinolines, pyridines, benzofurans, and furan to access the corresponding heterocycles, important molecules present in fine chemicals, agrochemicals, and pharmaceuticals. The catalyst is highly selective, acting only on the heteroaromatic ring, and not interfering with other reducible functional groups.
A Rhodium Nanoparticle-Lewis Acidic Ionic Liquid Catalyst for the Chemoselective Reduction of Heteroarenes. -Rhodium nanoparticles stabilized with [bmim]BF 4 ionic liquid in combination with the Lewis acidic chlorozincate of the formula (ZnCl2)0.67-[bmim]Cl is found to be an efficient catalyst system for the highly chemoselective ring-hydrogenation of functionalized quinolines, pyridines, and furans. -(KARAKULINA, A.; GOPAKUMAR, A.; AKCOK, I.; ROULIER, B. L.; LAGRANGE, T.; KATSYUBA, S. A.; DAS*, S.; DYSON, P. J.; Angew. Chem., Int. Ed. 55 (2016) 1, 292-296, http://dx.doi.org/10.1002/anie.201507945 ; Inst. Sci. Ing. Chim., Ec. Polytech. Fed. Lausanne, CH-1015 Lausanne, Switz.; Eng.) -Mais 19-036
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