BACKGROUND: The usefulness of numerical modelling of a patient’s cardiovascular system is growing in clinical treatment. Understanding blood flow mechanics can be crucial in identifying connections between haemodynamic factors and aortic wall pathologies. OBJECTIVE: This work investigates the haemodynamic parameters of an ascending aorta and ascending aortic aneurysm in humans. METHODS: Two aortic models were constructed from medical images using the SimVascular software. FEM blood flow modelling of cardiac cycle was performed using CFD and CMM-FSI at different vascular wall parameters. RESULTS: The results showed that highest blood velocity was 1.18 m/s in aorta with the aneurysm and 1.9 m/s in healthy aorta model. The largest displacements ware in the aorta with the aneurysm (0.73 mm). In the aorta with the aneurysm, time averaged WSS values throughout the artery range from 0 Pa to 1 Pa. In the healthy aorta, distribution of WSS values changes from 0.3 Pa to 0.6 Pa. CONCLUSIONS: In the case of an ascending aortic aneurysm, the maximum blood velocity was found to be 1.6 times lower than in the healthy aorta. The aneurysm-based model demonstrates a 45% greater wall displacement, while the oscillatory shear index decreased by 30% compared to healthy aortic results.
This work aimed to perform a numerical study of aortic hemodynamics and evaluate both Newtonian and non-Newtonian blood flow parameters in an ascending aortic aneurysm model.An aortic model was reconstructed from a medical computed tomography (CT) image, and finite element method laminar blood flow modelling was performed using different blood parameters. The inflow boundary conditions were defined as a flow profile, and the outlet boundary conditions were defined as the pressure at each outlet. The first simulation was calculated by considering blood as a Newtonian fluid, while in the second simulation, using the Carreau model, blood was assumed to be a non-Newtonian fluid.The results showed that average systolic and diastolic velocities were 2% and 9% higher, respectively, for the non-Newtonian fluid. In addition, the wall shear stress (WSS) values on the surface of the aneurysm were 30% higher during systole in the non-Newtonian simulation, while the average WSS on the artery surface in diastole was 20% higher for the Newtonian fluid.
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