Community pharmacist-led interventions have been shown to contribute to improved adherence and better disease control. Future research should attempt to better understand which particular intervention components make the greatest contribution towards improving adherence and health outcomes, for patients with different medical conditions.

miR-146a and miR-155 may be considered as possible novel biomarkers for periodontitis in non-diabetic and type 2 diabetic patients.

We present the Raman scattering results on layered semiconducting ferromagnetic compound CrSiTe3. Four Raman active modes, predicted by symmetry, have been observed and assigned. The experimental results are supported by DFT calculations. The self-energies of the A 3 g and the E 3 g symmetry modes exhibit unconventional temperature evolution around 180 K. In addition, the doubly degenerate E 3 g mode shows clear change of asymmetry in the same temperature region. The observed behaviour is consistent with the presence of the previously reported short-range magnetic order and the strong spin-phonon coupling.

We present results from light scattering experiments on tetragonal FeS with the focus placed on lattice dynamics. We identify the Raman active A1g and B1g phonon modes, a second order scattering process involving two acoustic phonons, and contributions from potentially defect-induced scattering. The temperature dependence between 300 and 20 K of all observed phonon energies is governed by the lattice contraction. Below 20 K the phonon energies increase by 0.5-1 cm −1 thus indicating putative short range magnetic order. Along with the experiments we performed latticedynamical simulations and a symmetry analysis for the phonons and potential overtones and find good agreement with the experiments. In particular, we argue that the two-phonon excitation observed in a gap between the optical branches becomes observable due to significant electronphonon interaction.

We present Raman spectroscopy measurements of van der Waals bonded ferromagnet Fe3−xGeTe2, together with lattice dynamics. Four out of eight Raman active modes are observed and assigned, in agreement with numerical calculations. Energies and line-widths of the observed modes display unconventional temperature dependence at about 150 K and 220 K followed by the non-monotonic evolution of the Raman continuum. Whereas the former can be related to the magnetic phase transition, origin of the latter anomaly remains an open question.

Type 2 diabetic participants had decreased MEL in hDP. At pharmacological concentrations, MEL is not cytotoxic for hDPCs and normalizes iNOS and SOD activity levels in hyperglyceamic hDPCs suggesting its antioxidant and protective effects in human dental pulp tissue under hyperglycaemia.

In this study, we demonstrate for the first time, that a discrete metal-oxo cluster α-/β-K6P2W18O62 (WD-POM) exhibits superior performance as a computed tomography (CT) contrast agent, in comparison to the standard contrast agent iohexol. A toxicity evaluation of WD-POM was performed according to standard toxicological protocols using Wistar albino rats. The maximum tolerable dose (MTD) of 2000 mg/kg was initially determined after oral WD-POM application. The acute intravenous toxicity of single WD-POM doses (1/3, 1/5, and 1/10 MTD), which are at least fifty times higher than the typically used dose (0.015 mmol W kg−1) of tungsten-based contrast agents, was evaluated for 14 days. The results of arterial blood gas analysis, CO-oximetry status, electrolyte and lactate levels for 1/10 MTD group (80% survival rate) indicated the mixed respiratory and metabolic acidosis. The highest deposition of WD-POM (0.6 ppm tungsten) was found in the kidney, followed by liver (0.15 ppm tungsten), for which the histological analysis revealed morphological irregularities, although the renal function parameters (creatinine and BUN levels) were within the physiological range. This study is the first and important step in evaluating side effects of polyoxometalate nanoclusters, which in recent years have shown a large potential as therapeutics and contrast agents.

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