Background: Drug-induced esophagitis is an uncommon diagnosis in the pediatric population. The following is a report of six adolescents with L-arginine-induced esophagitis. Case reports: All patients were under treatment with L-arginine for short stature. After using the prescribed medication for 1-3 months, all cases started with severe retrosternal pain, odynophagia, and dysphagia. The upper gastrointestinal endoscopies showed ulcers located in the mid esophageal mucosa. Conclusions: In the presence of acute severe odynophagia, dysphagia, and retrosternal pain, drug-induced esophagitis should be considered as a possible diagnosis. Treatment includes liquid diet, pain control, sucralfate, omeprazole, and interruption of L-arginine.In addition, the physician should explain preventive measures focused on patient and family education on the drug side effects and precise instructions on how to take medications, as well as a careful balance of risk and benefits of any medication. At present, there are no clinical trials that support the use of L-arginine in treatment of short stature.
Antecedentes: El síndrome de enterocolitis inducida por proteínas de los alimentos es una alergia alimentaria poco frecuente no mediada por IgE. El síntoma principal son los vómitos una a cuatro horas después del consumo del alimento causal.Caso clínico: Varón de ocho meses, sin antecedentes heredofamiliares de alergia, con antecedentes personales patológicos de alergia a la proteína de la leche de vaca. A los siete meses había presentado gastroenteritis aguda con choque mixto y a los ocho meses, gastroenteritis aguda y deshidratación moderada; en ambos eventos hubo consumo de arroz previo al inicio de los síntomas. Al descartar etiología infecciosa y otras causas de vómitos y deshidratación, se formuló el diagnóstico de síndrome de enterocolitis inducida por proteínas de los alimentos, secundario a proteína de arroz, que se corroboró con prueba de parche.Conclusión: El síndrome de enterocolitis inducida por proteínas de los alimentos debe ser considerado en el diagnóstico diferencial de gastroenteritis recurrente, principalmente en cuadros graves sin causa infecciosa identificada.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.