Background. SARS-CoV-2 infection was analyzed according to previous metabolic status and its association with mortality and post-acute COVID-19. Methods. A population-based observational retrospective study was conducted on a cohort of 110,726 patients aged 12 years or more who were diagnosed with COVID-19 infection between June 1st, 2021, and 28 February 2022 on the island of Gran Canaria, Spain. Results. In the 347 patients who died, the combination of advanced age, male sex, cancer, immunosuppressive therapy, coronary heart disease, elevated total cholesterol and reduced high-density lipoprotein cholesterol (HDL-C) was strongly predictive of mortality (p < 0.05). In the 555 patients who developed post-acute COVID-19, the persistence of symptoms was most frequent in women, older subjects and patients with obstructive sleep apnea syndrome, asthma, elevated fasting glucose levels or elevated total cholesterol (p < 0.05). A complete vaccination schedule was associated with lower mortality (incidence rate ratio (IRR) 0.5, 95%CI 0.39–0.64; p < 0.05) and post-acute COVID-19 (IRR 0.37, 95%CI 0.31–0.44; p < 0.05). Conclusions. Elevated HDL-C and elevated total cholesterol were significantly associated with COVID-19 mortality. Elevated fasting glucose levels and elevated total cholesterol were risk factors for the development of post-acute COVID-19.

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Summary Epidemiological, Aethiological and Pathological Studies of Respiratory Disease in Lambs in the South of Spain. Between 1991 and 1993, it was observed epidemiologically that respiratory disturbances in lambs are associated with high temperatures during the summer. The aethiological agent isolated is principally Mycoplasma ovipneumoniae; moreover, Actinobacillus pleuropneumoniae biovar A has been isolated in a high number of samples. Histopathologically, an interstitital bronchopneumonia was the main lesional finding; this lesion is associated with previous mycoplasma infection. Resumen En este trabajo se realiza un estudio epidemiológico, etiológico y lesional de la afecciones respiratorias que afectan a los corderos criados de forma intensiva en el Sur de España. Epidemiológicamente, se comprobó la estacionalidad de estos problemas respiratorios, asociándose al incremento de la temperatura ambiental durante la época estival. Mycoplasma ovipneumoniae fue el agente etiológico más frecuentemente aislado, seguido de Actinobacillus pleuropneumoniae biovar A. Histopatológicamente, se comprobó el desarrollo de una bronconeumonía intersticial como la principal forma lesional asociada a estos procesos respiratorios, lo que indica una clara implicación de los micoplasmas en la iniciación de este tipo de patología.

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