Defective protein kinase C (PKC) has been implicated in impaired Na+ ,K + -ATPase activity in the sciatic nerve of streptozotocin-induced diabetic rats . In the present study, a, ßl, ßll,~y, S, and e isoform-specific antibodies were used in parallel to the measurement of compound PKC activity for the characterization of PKC distribution and isoform expression in sciatic nerves of normal and diabetic rats . To distinguish isoform expression between the axonal and glial compartments, PKC isoforms were evaluated im nerves subjected to Wallerian degeneration and in a pure primary Schwann cell culture . a, ßl, ßII, S, and

Actinomycosis should be considered in patients with pelvic mass or abdominal wall mass that mimics a malignancy. Antibiotic therapy is the first treatment choice and makes a more invasive surgical management unnecessary.

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