This paper presents the design of an extremely lowenergy biosensing platform that utilizes voltage to time conversion and time-mode signal processing to sense and accommodate electrophysiological biosignals that will be later sent remotely using a simple and low power communication scheme. The electrode input is fed to a chain of monostable multivibrators used as analog-to-time converters, which create time pulses whose widths are proportional to the input signal. These pulses are transmitted to an external receiver by means of singlepulse harmonic modulation as the communication scheme, at a carrier frequency of 10 MHz. The platform is designed to be implemented in a standard 0.18 µm IC process with an energy dissipation per sample per channel of 42.72 pJ, including communication, operating from a supply voltage of 0.6V with an input referred noise of 12.3µVrms. The resulting SNR for OSR=256 is 35.19 dB, and the system's power consumption at a sampling and communication rate of 256 Hz is 10.94 nW.
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