Objectives
To describe the characteristics of patients who undergo balloon pulmonary angioplasty (BPA) for inoperable chronic thromboembolic pulmonary hypertension (CTEPH) and report the mid‐term outcomes.
Background
BPA has been recently introduced in Latin America. Mid‐term results have not been published.
Methods
Prospective Chilean Registry of inoperable CTEPH patients who underwent BPA. Clinical variables were analyzed at baseline, after each procedure and at follow‐up. Hemodynamic variables were recorded before and after the last BPA.
Results
Between August 2016 and September 2019, 22 patients (17 women), 59 ± 12.7 years, underwent 81 BPA and were followed for as long as 33.1 months (mean 17.3 ± 7.5). Mean pulmonary artery pressure decreased by 17.4% (51.1 ± 12 vs. 42.2 ± 13 mmHg, p = .001), pulmonary vascular resistance by 23.9% (766.7 ± 351 vs. 583 ± 346 dynes/s/cm−5, p = .001), cardiac index increased by 8% (2.3 ± 0.54 vs. 2.5 ± 0.54 L/min/m2, p = .012), N‐terminal pro‐B‐type natriuretic peptide decreased by 73.8% (1,685 ± 1,045 vs. 441.8 ± 276 pg/dl, p = .006), and 6‐min walk distance improved by 135 m (316.7 ± 94 vs. 451.1 ± 113 m, p = .001). One patient (4.5%) developed lung reperfusion injury and four patients (18.2%) had minor bleeding (hemoptysis), after the procedure. There was no mortality associated with BPA.
Conclusions
Our results confirm that BPA for inoperable CTEPH is a relatively safe procedure that improves clinical and hemodynamic parameters in the mid‐term. This therapy should be considered as an alternative, mainly in places where access to PAH therapy or surgery is restricted.
La revascularización coronaria híbrida busca combinar el beneficio de las técnicas quirúrgicas y percutáneas para un manejo óptimo de pacientes seleccionados con enfermedad coronaria obstructiva multivaso. Esto permite asociar el beneficio del puente de arteria mamaria interna izquierda a la arteria descendente anterior (ADA) y combinarlo con el implante de stents en lesiones no-ADA. El objetivo de este tra-bajo es hacer una revisión de la literatura disponible con énfasis en sus resultados clínicos comparados con la estrategia convencional. Palabras clave: Revascularización híbrida coronaria, enfermedad de arteria coronaria, cirugía de bypass de arteria coronaria, intervención coronaria percutánea.
La coronarioectasia difiere en los factores de riesgo clásicos... Fuensalida A., et al. La coronarioectasia difiere en los factores de riesgo clásicos... Fuensalida A., et al. La coronarioectasia difiere en los factores de riesgo clásicos... Fuensalida A., et al.
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