METHODS AND MATERIALSCriteria for Therapy. The plan for treating patients in shock was to administer phenylephrine hydrochloride (Neo-Synephrine) or other pressor amines by the intramuscular or intravenous route intermittently as indicated. If the systolic blood pressure was elevated to above 100 mm. Hg and satisfactorily maintained, further therapy was withheld. On recurrence of shock similar medication was employed through one to three episodes. Norepinephrine by continuous drip was instituted if (1) the patient was known to have been in shock longer than one hour, (2) the initial episode of shock was severe with systolic pressure below 80 mm. Hg for at least 15 minutes, (3) more than three transient episodes of shock had occurred within 12 hours, (4)

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