In 1917, after scientific breakthroughs allowed for the early detection of bovine tuberculosis, the USDA began a campaign to eradicate the disease. Agents inspected nearly every cattle farm in the country and condemned roughly 4 million reactors to slaughter without full compensation. This article analyzes how the eradication program functioned, how incentives were aligned to ensure widespread participation without excessive moral hazard problems, and why the United States led most European nations in controlling the disease. The U.S. campaign was a spectacular success, reducing human suffering and death and yielding benefits in the farm sector alone that exceeded ten times the cost.

The boll weevil is America's most celebrated agricultural pest. We analyze new county-level panel data to provide sharp estimates of the time path of the insect's effects on the southern economy. We find that in anticipation of the contact, farmers increased production, attempting to squeeze out one last large crop. Upon arrival, the weevil had a large negative and lasting impact on cotton production, acreage, and especially yields. In response, rather than taking land out of agricultural production, farmers shifted to other crops. We also find striking effects on land values and population movements.

The Intergovernmental Panel on Climate Change projects that temperatures in the major grain-growing areas of North America will rise by 3–4 °C by 2100. Such abrupt changes will create major challenges, significantly altering the area suitable for wheat. The historical record offers insight into the capability of agriculture to adapt to climatic challenges. Using a new county-level dataset on wheat production and climate norms, we show that during the 19th and 20th centuries North American grain farmers pushed wheat production into environments once considered too arid, too variable, and too harsh to cultivate. As summary measures, the median annual precipitation norm of the 2007 distribution of North American wheat production was one-half that of the 1839 distribution, and the median annual temperature norm was 3.7 °C lower. This shift, which occurred mostly before 1929, required new biological technologies. The Green Revolution associated with the pioneering work of Norman Borlaug represented an important advance in this longer process of biological innovation. However, well before the Green Revolution, generations of North American farmers overcame significant climatic challenges.

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