The success of the endodontic treatment depends on the microbial suppression in the root canal and periapical region. Endodontic instrumentation alone cannot achieve a sterile condition. With the advent of non-instrumentation endodontic treatment and lesion sterilization and tissue repair, local application of antibiotics has been investigated. Triple antibiotic paste (TAP) containing metronidazole, ciprofloxacin, and minocycline has been reported to be a successful regimen in controlling the root canal pathogen and in managing non-vital young permanent tooth. This paper reviews the existing literature on biocompatibility, efficiency, drawbacks of TAP in endodontic therapy and pulp revascularization.
A syndrome is a medical condition that is characterized by a particular group of signs and symptoms, involving several organ systems. Oligodontia is defined as the developmental absence of six teeth or more, excluding third molars. Oligodontia can be classified as syndromic or nonsyndromic. Nonsyndrome oligodontia is a developmental dental anomaly without involvement of other organs. The consequences of missing teeth include abnormal occlusion or altered facial appearance, which can cause psychological distress in some patients. The management of oligodontia usually requires a multidisciplinary approach. The present article reports a case of oligodontia in siblings of the same family with no apparent systemic abnormalities.
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