We have developed a novel micro optical diffusion sensor (MODS) based on a laser induced dielectrophoresis (LIDEP) enabling small sample volume, high-speed measurement and on-site sensing of the protein conformation. This paper reports the measurement principle, chip design, and the validity of the proposed method. In order to verify the applicability of MODS, we confirmed the sinusoidal concentration distribution of polystyrene beads in distilled water generated by LIDEP force. The decay time of the diffusion of the concentration distribution agreed well with the theoretical calculation. As a result, the applicability of MODS as the diffusion coefficient measurement method was verified.
We have developed a rollable multi-touch pressure sensor that works with a radius down to 5 mm, a high dynamic range of 1-300 kPa, and a spatial resolution down to 3 mm. This was achieved using a novel sensor with an organic-deformation layer. It will enable multi-directional user interactions.
We have developed a novel micro optical diffusion sensor (MODS) based on laser-induced dielectrophoresis (LIDEP), which enables rapid measurement with a small sample volume and on-site sensing of protein conformation. This paper presents the measurement principle, the chip design, and the validity of the proposed method. To verify the applicability of MODS, we confirmed a sinusoidal concentration distribution of polystyrene beads in a surface-modified microchannel generated by LIDEP force. The decay time of the diffusion of the concentration distribution agreed well with theoretical calculations, confirming the applicability of MODS as a technique for measuring the diffusion coefficient.
Micro-electro mechanical systems (MEMS) biochips realizing high-speed and high-efficiency of reaction and analysis attract much attention in medical as well as chemical fields. Especially, the miniaturized devices enabling small sample volume, arrayed, and portable measurement may become a powerful tool for material analysis and process control. We have proposed a novel micro optical diffusion sensor (MODS) which enables small sample volume, highspeed and non-contact measurement of diffusion coefficient of liquid sample. MODS consists of a pair of transparent electrodes (Al-doped Zinc oxide: AZO), a photoconductive layer (amorphous silicon: a-Si:H), two MEMS mirrors and excitation and probing fibers for inducing and detecting concentration distribution. The initial concentration distribution of sample is created by an opto-dielectrophoretic (opto-DEP) manipulation along with a sinusoidal pattern of irradiated beam on a photoconductive layer. In the present paper, the measurement principle is proposed, and the preliminary experiment using a bench top apparatus is reported.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.