Background: Barriers to uptake of cataract surgery in a developing country like Nigeria are numerous, most researches focus on patient related factor like financial constraint however this study aims to assess the systemic co-morbidities that act as a barrier to uptake of cataract surgery at University College Hospital Ibadan, Oyo-State, Nigeria so that measures can be put in place to minimize this effect and thereby increase cataract surgery uptake in the centre.Results: Three hundred and eighty-eight cataract patients participated in the study. The mean age of the patients was 66.6±11.2years with a range of 40 to 90 years. More than half (66.2%) of the study participants had systemic comorbidities. Poorly controlled systemic hypertension is the most common cause of systemic co-morbidities that constitute significant barrier to uptake of cataract surgery.Conclusion: There is a need for good and close collaboration between the physicians and the ophthalmologists so as to make management of cataract patients with systemic co-morbidities easier and more efficient at the Eye
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