Mobility and accessibility provided by the transport system have been playing a major role in shaping countries, influencing the location of social and economic activity, the form and size of cities, and the style and pace of life by facilitating trade, permitting access to people and resources, and enabling greater economies of scale, worldwide and throughout history. This study examined the challenges, prospect and opportunities of air transport operation in Nigeria. Data was obtained from the administration of questionnaires to 170 aviation workers at Muritala Muhammed Airport in Lagos, who were randomly selected. Simple descriptive statistics, Chi-Square and Analysis of variance were employed. The findings show that private investment is critical to sustainable air transport infrastructure in Nigeria. Based on available facts and figure, it can be concluded that government should create an enabling environment for the airlines and come up with maintenance, repair and overhaul policy, as well as address the foreign exchange challenge facing airlines in Nigeria.
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