Objectives: To determine the clinical and demographical profile of corona-virus illness among Tablighi Jamaat and Zaireen kept in quarantine / isolation center at Sukkur and Hyderabad Sindh. Methods: The cross-sectional descriptive study (late March-2020 to mid of April-2020) was conducted at Diagnostic & Research Laboratory LUMHS Jamshoro / Hyderabad. All the suspected cases for COVID-19 were recruited and screened for corona virus infection. The study explored the data of the suspected and diagnosed (confirmed) case of COVID-2019 (Tablighi Jamaat and Zaireen) reported by Diagnostic Research Laboratory Liaquat University of Medical and Health Sciences (LUMHS) Jamshoro who belonged to various parts of the country in general and province Sindh in particular. All the individuals regardless of age and gender presented either as asymptomatic, critical ill or having non-specific symptoms as fever, flu, cough; sore throat and shortness of breath were screened for COVID-19 by real time PCR after taking informed consent whereas the frequency / percentages (%) and means ±SD computed for study variables. Results: During study period total 920 patients were explored and screened for Corona virus infection. The mean ± SD for age (yrs) of overall population of city Sukkur and Hyderabad was 57.83±8.84 and 59.62±9.72 respectively. The 700 people from Sukkur city was screened and out of them 276 (39.4%) were positive and 424 (60.5) were negative while the cure rate was 245 (88.7%) along with mean ± SD for recovery time was 9.41±2.97. The 220 people from Hyderabad city was screened and out of them 106 (48.1%) were positive and 114 (51.8%) were negative while the cure rate was 106 (100%) along with mean ± SD for recovery time was 11.54±3.42. The majority of cases at both centers were asymptomatic (90%), symptomatic (7%) and critically ill (3%). The mortality accounted for 2.8% cases at Hyderabad isolation center and all were having smoking history and co-morbidities as ischemic heart diseases, diabetes mellitus, obstructive lung disease and cerebrovascular accident whereas no mortality was observed at Sukkur isolation center. Conclusion: RT-PCR measure allowed fast, delicate, and explicit discovery of SARS-CoV in biochemical diagnosis. The majority of cases at both centers were asymptomatic while the mortality was identified in 2.8% cases (having co-morbidities) at Hyderabad isolation center whereas no mortality was observed at Sukkur isolation center. doi: https://doi.org/10.12669/pjms.36.COVID19-S4.2829 How to cite this:Ujjan ID, Devrajani BR, Ghanghro AA, Shah SZA. The clinical and demographical profile of Coronavirus illness: The tale of Tablighi Jamaat and Zaireen in Quarantine / Isolation center at Sukkur and Hyderabad. Pak J Med Sci. 2020;36(COVID19-S4):---------. doi: https://doi.org/10.12669/pjms.36.COVID19-S4.2829 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background: Reports on burden of hepatitis C and hepatitis B virus (HCV/HBV) are a big challenge for district to minimize the transmission of associated risk factors. Study was conducted to know the prevalence of HCV/HBV infection in pregnant women and their blood donors attended a surgical referral clinic for cesarean delivery. Objective: To determine the prevalence of HCV/HBV infection among pregnant women and their blood donors. Methods: A cross-sectional analytical study (record review) of all pregnant women and their blood donors (family members) was conducted from 10th to 15th February 2015 at a private surgical clinic in district Naushahro Feroze. Data from 1st January to 31st December 2014 gathered on results of blood screening used by ELISA test. Results: Of 175 women aged 15–52 years, 13% (n = 22) tested positive (13 HCV; 9 HBV) besides these a total of 656 blood donors aged 16–40 years reported for blood donations and were 22% (n = 145) tested positive (80 HCV; 65 HBV). The highest positivity rate was seen in women aged 25 years or less (26%) compared with those aged above 25 years (9%) OR = 3.02 (95% CI 1.03 to 9.98). Statistically significant difference was identified between ages of donors who were aged below 25 years were high positivity rate (30%) compared to above 25 years positive for hepatitis infection (24%) OR = 1.15. 02 (95% CI 1.01 to 2.34). Conclusions: One in eight pregnant women attending surgical clinic for cesarean delivery and one in five blood donors who came to attend for bleed has evidence of HCV/HBV infection. These HCV/HBV positive mothers may be at increased risk of transmitting HCV/HBV infection to their unborn babies. We suggest that all pregnant women attending 1st antenatal care be tested for HCV/HBV infection; exposed babies need to receive HBV vaccines at birth. Further molecular studies on risk factors needed in these settings.
Background: Reports on burden of hepatitis C and hepatitis B virus (HCV/HBV) are a big challenge for district to minimize the transmission of associated risk factors. Study was conducted to know the prevalence of HCV/HBV infection in pregnant women and their blood donors attended a surgical referral clinic for cesarean delivery. Study was therefore undertaken to determine the prevalence of HCV/HBV infection among pregnant women and their blood donors.Methods & Materials: A cross-sectional analytical study (record review) of all pregnant women and their blood donors (family members) was conducted from 10th to 15th February 2015 at a private surgical clinic in district Naushahro feroze. Data from 1st January to 31st December 2014 gathered on results of blood screening used by ELISA test.Results: Of 175 women aged 15-52 years, 13%(n=22) tested positive (13 HCV; 9 HBV) besides these a total of 656 blood donors aged 16-40 years reported for blood donations and were 22%(n=145) tested positive (80 HCV; 65 HBV). The highest positivity rate was seen in women aged 25 years or less(26%) compared with those aged above 25 years (9%) OR=3.02 (95% CI 1.03 to 9.98). Statistically significant difference was identified between ages of donors who were aged below 25 years were high positivity rate(30%) compared to above 25 years positive for hepatitis infection(24%) OR= 1.15. 02 (95% CI 1.01 to 2.34). Conclusion:One in eight pregnant women attending surgical clinic for cesarean delivery and one in five blood donors who came to attend for bleed has evidence of HCV/HBV infection. These HCV/HBV positive mothers may be at increased risk of transmitting HCV/HBV infection to their unborn babies. We suggest that all pregnant women attending 1st antenatal care be tested for HCV/HBV infection; exposed babies need to receive HBV vaccines at birth. Further molecular studies on risk factors should be carried out at these settings.
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