speakers shared their experiences from Egypt and the US. Discussions focused on prenatal versus postnatal, early-onset versus late-onset, and hospital versus community acquired neonatal infections. Five topics represented high priorities for research in Egypt: 1) maternal vaginal colonisation patterns and maternal vaginal screening practices for common and emerging pathogens, 2) risk factors associated with hospital-acquired infections in delivery rooms and neonatal intensive care units, 3) antimicrobial resistance among pathogens affecting newborns in intensive care units, 4) education and compliance with infection control measures among staff, and 5) presentation and risk factors for neonatal infections associated with home deliveries. Webinar conferences will be conducted with each team to mature their project. A second workshop will be organised to develop a grant proposal for each research project to be submitted to international funding agencies. Conclusion To address neonatal infections related mortality and morbidities, stakeholders involved in the care of the newborns in Egypt need to develop a prioritised future research agenda. A central taskforce need to facilitate the assembly of multicenter, multidisciplinary teams across the country to study these issues in collaboration with international expertise and funding resources. Introduction Early Onset Neonatal Sepsis (EONS) is a major contributor to morbidity and mortality in ELBW infants. Admission surface swab cultures (SSC) form part of admission surveillance cultures, however its place in the management of EONS is questionable. Objective To determine: PO-0555• Sensitivity, specificity and positive predictive value of SSC.• If culture result would reflect on mean CRP value in first 72 hrs.• If maternal swabs and mode of delivery correlated with microbiological result in the baby. Method• Retrospective cohort study.• All inborn ELBW infants admitted into a Level 3 NICU from January 2010-December 2013.• Maternal swabs; mode of delivery; infants SSC, blood cultures and mean CRP (within 72 h) were reviewed. Result• 161 ELBW infants were admitted and all had admission SSC, CRPs and blood cultures.• 25 of 161 (15.5%) had positive SSC (Figure 1) of which 5 were mixed culture results.• 11 of 161 (6.8%) had EONS (positive blood cultures) ( Table 1).• 4 of 25 (16%) of positive SSC had correlating blood cultureall of which were E coli; 1 subject had positive SSC and blood culture but did not correlate.Abstract PO-0555 Figure 1 Bacteria grown from skinj swab Abstract PO-0555 • There was a statistically significant association between mode of delivery and positive culture result, 2(1) = 10.263, p = 0.001 (Figure 2). • Sensitivity, specificity and positive predictive value for skin swab were 36.3%, 86.7% and 16% respectively. Conclusions• Routine SSC is inefficient in predicting the pathogen responsible for sepsis among premature neonates.• E coli was the predominant organism in the study and 37% of babies with positive SSC had E. coli sepsis (blood culture).• M...
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