Background: As individuals grow older, they may be more susceptible to chronic diseases, which can affect their overall health. Periodontitis, for instance, is one of the most common oral diseases that result from prolonged exposure to pathogens. The main etiology of periodontitis is dental biofilms, but several risk factors may also affect the progression of the disease. Purpose: The study aimed to determine whether there was an association between age, gender and education level and the severity of periodontitis using the 2017 American Academy of Periodontology (AAP) classification. Methods: A retrospective analytical study was used to determine the stage and grade of periodontitis in relation to age, gender and education level. Secondary data in the form of medical record status was analysed using software applications. Results: The distribution of periodontitis was 66.7% in pre-elderly patients (45–59 years), 61.5% in male subjects and 39.7% in individuals with middle education levels. Using chi-square analysis, the severity of periodontitis showed a statistically significant correlation with age (p=0.01) and gender (p=0.003). In contrast, the level of education was not statistically correlated to the severity of periodontitis (p=0.887). The percentage of stage IV grade B was highest in elderly patients (65.38%), while stage IV grade C was the highest in male subjects (41.67%). Conclusion: The study showed that age and gender significantly influenced the occurrence and severity of periodontitis, while education level showed the opposite.
Hydroxyapatite has been widely used as bone graft materials in periodontics. However, hydroxyapatite is still considered costly, and many of them are imported. Hydroxyapatite manufacturers from natural sources could be an affordable alternative for periodontal regeneration therapy. Pugilina cochlidium and Babylonia spirata, L are the natural sources with high calcium carbonate. The two clamshells are easily found in Indonesia but their usage is still limited as hydroxyapatite materials. This study aims to synthesize the hydroxyapatite with sol-gel method from Pugilina cochlidium and Babylonia spirata, L as bone graft materials candidates.
Periodontitis is one of most common oral disease. Chronic periodontitis is characterised by gingival inflamation, periodontal pocket, lost of attachment, and alveolar bone loss. Smoking is a risk factor of periodontal disease that has direct effect to periodontal tissue. Smoking prevalence in Indonesia during 2013 was about 56,7% among men and about 1,9% among women. Smoking modifies the periodontal microbial challenge and host cytokine levels. Some studies showed that smoker has greater alveolar bone loss than non-smoker, and teeth that have the greatest alveolar bone loss are incisor and followed by molar. The aim of this study is to know the upper incisor and upper molar alveolar bone loss differences between smoker and non-smoker patient with chronic periodontitis. The study’s samples are 92 chronic periodontitis statuses and 200 periapical radiographs that selected by purposive sampling techinque. This study will measure the distance between cementoenamel junction to alveolar bone crest, cementoenamel junction to tooth apex, and alveolar bone loss percentage at upper incisor and upper molar. To compare the differences upper incisor and upper molar alveolar bone loss at patient with chronic periodontitis between smoker and non-smoker will be analyzed by independent t test and Mann-Whitney U test. The result showed that smoker has greater alveolar bone loss than non-smoker. There is no significant differences at upper incisor alveolar bone loss and there is significant differences at upper molar alveolar bone loss between smoker and non-smoker patient with chronic periodontitis.
Chronic periodontitis is an inflammatory disease which is characterized by the absence of pain and develops slowly, loss of attachment and resorption of bones that causes teeth to mobile and loose. Some markers responsible for the inflammatory process include cytokines, such as Interleukin-6 (IL-6), as one of the inflammatory cytokines, plays an important role in the inflammatory response of the periodontium. To handle the case of periodontitis, can be done by scaling and root planning (SRP) and can be combined with systemic ingredients and the application of herbal ingredients. One of the natural ingredients that has been used in wound healing is binahong leaves. In this study using 3% binahong leaves gel extract was applied to subgingival to reduce levels of IL-6 and periodontal status. In this study, using 16 samples, were divided into 2 groups: ie 8 samples as a test group, and 8 samples as a control group. IL-6 levels were examined after scaling and root smoothing. Statistically, there was a significant decrease in IL-6 levels in the gingival sulcus fluid after scaling and root planing (SRP) in periodontitis patients with ap values <0.05. There was a significant decrease in measurement of IL-6 levels in the test and control groups after application of subgingival gel of binahong leaves extract (Andredera cordifolia (Ten.) Steenis) 3% in patients with chronic periodontitis. there was a significant decrease in IL-6 levels in the gingival sulcus fluid after scaling and root planing (SRP) in periodontitis patients with ap value <0.05.
Coronary Heart Disease (CHD) is the major cause of death in most countries in the world. Gram-positive and Gram-negative bacteria have been identified in bacteremia cases and known to have a role in various vascular diseases, including Streptococcus sanguinis which is most frequently isolated from endocarditis patients and often associated with CHD. The purpose of this study was to analyze the number of Streptococcus sanguinis isolated from dental plaque and saliva of subjects with and without CHD. Bacterial colonies isolated from the dental plaque and saliva of 16 subjects without CHD and 8 subjects with CHD were planted in Mitis salivarius agar, and then the DNA was extracted and quantified with a Real-Time PCR technique using 16S rRNA specific primers. The quantification of Real-Time PCR showed that there was a difference in the number of S. sanguinis between the two groups of subjects, but an unpaired T-test showed that the difference was not statistically significant. Furthermore, the number of S. sanguinis from dental plaque in CHD subjects tends to be higher than that of non-CHD subjects whereas the number of S. sanguinis from saliva in non-CHD subjects tends to be higher than that of CHD subjects.
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