Agglutinative languages (i.e., languages in which words are formed by joining morphemes together; e.g., Hungarian, Turkish, Basque) are an excellent testing ground for psycholinguistic research in some of the key issues in lexical access. At present, there are several useful databases for computing a number of relevant psycholinguistic statistics in nonagglutinative languages (for English, see Coltheart, 1981;Davis, 2005; for French, see New, Pallier, Brysbaert, & Ferrand, 2004; for Spanish, see Davis & Perea, 2005), but none for those in agglutinative languages. Here, we present both a word frequency list (for word forms and lemmas) and an application for computing a wide variety of psycholinguistic statistics (so that relevant variables can be manipulated and/or controlled) in an agglutinative language that is of special interest to researchers in psycholinguistics: Basque.Basque is a pre-Indo-European language-with no demonstrable genetic relationship to any other living language-that is spoken at the western end of the Pyrenees, close to the Spanish-French border. Basque (Euskara in Basque) holds co-official language status (together with Spanish) in the Basque Autonomous Community and in some parts of Navarre. It is spoken by more than 700,000 people. Research in Basque is of special interest not just because of its very long history (its origins are unknown), but also because of its distinctive morphology and syntax.The interest of Basque for morphological studies is based on the fact that Basque is an agglutinative language and, as such, has a high proportion of inflected words (e.g., etxe [house] [homeowner]). Indeed, compound words are often formed by several lexemes (e.g., the Basque word for "argument"[eztabaida] can be decomposed as ez-da-bai-da, which literally means "It is, it isn't"). The interest of Basque for syntax studies is due to the fact that Basque has not only rich inflectional morphology but also overt case markers, including up to three agreement markers on the inflected verb (marking subject, object, and dative agreement; e.g., daramazkiot ["I'm carrying (now) these (pl.) We describe a Windows program that enables users to obtain a broad range of statistics concerning the properties of word and nonword stimuli in an agglutinative language (Basque), including measures of word frequency (at the whole-word and lemma levels), bigram and biphone frequency, orthographic similarity, orthographic and phonological structure, and syllable-based measures. It is designed for use by researchers in psycholinguistics, particularly those concerned with recognition of isolated words and morphology. In addition to providing standard orthographic and phonological neighborhood measures, the program can be used to obtain information about other forms of orthographic similarity, such as transposed-letter similarity and embedded-word similarity. It is available free of charge from www .uv.es/mperea/E-Hitz.zip.
We present an automatic method to track individual nodule progression in a lung cancer mouse model. Fourteen A/J mice received an intraperitoneal injection of urethane. Respiratory-gated micro-CT images of the lungs were taken 8, 22, and 37 weeks after injection, at which 195, 585 and 636 nodules were manually detected. The three images from every animal were registered and their nodules matched with average accuracy of 97.2%. All nodules detected at week 8 were then tracked until week 37, and volumetrically segmented to characterize the growth rate and doubling rate. Our framework is able to segment 92.9% of all nodules, ranging from the earliest stage (0.2mm) to advanced stage where nodule segmentation becomes challenging due to complex anatomy and nodule overlap. In conclusion, we showed the utility of the proposed framework to facilitate further research in pre-clinical lung cancer model.
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