The theory of medicine and food homology has a long history in China. Numerous traditional Chinese medicinal could be used as both medicine and food. Many flower medicinal materials also belong to the homology of medicine and food, such as Chrysanthemum morifolium, Lonicera japonica, Crocus sativus, and Lonicera macranthoides. They mainly contain flavonoids, organic acids, terpenoids, and other active ingredients, which have a variety of medicinal values, including anti‐inflammatory, anti‐tumor, and antioxidant. There are many formulations and functional foods containing these plants in Chinese medicine, which have a variety of nutritional and health effects on the human body. In this review, 10 widely used flowers were selected to review their pharmacological activities, prevention and treatment of related diseases and underlying mechanisms, and discussed the current limitations and future development prospects, hoping to provide references for the research on the development and utilization of natural medical flowers.
Practical applications
The “homology of medicine and food” flowers have a wide range of uses and are of great research value. In this paper, we introduce 10 “homology of medicine and food” flowers. Their active ingredients, pharmacological activities, and treatments for related diseases are reviewed, and the limitations and development prospects of the “homology of medicine and food” flowers are discussed. It is hoped that this will contribute to the development of the food and pharmacological fields.
Kaempferol (KPF) is a flavonoid compound, which has a variety of pharmacological activities, and widely exists in daily diet. However, its application is limited due to poor solubility. Citric acid (CA) is a common food additive with high solubility. In this study, solid dispersion (SD) was prepared with CA as the carrier to improve the solubility of KPF. KPF-CA-SD (weight ratio 1:20) was obtained by ultrasonic for 20 min at 40 °C. The in vitro dissolution of KPF in SD was increased from about 50% to more than 80%. The physicochemical characterizations were analyzed by X-ray diffraction, differential scanning calorimetry, Fourier transform infrared spectroscopy, and scanning electron microscope. In hyperuricemia mice, KPF-SD (equivalent to 100 mg/kg KPF) can effectively reduce serum uric acid and exert nephroprotective effects. In conclusion, the preparation of SD with CA might provide a safe and effective selection to facilitate application of KPF in food and medicine.
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