Background: Digital mammography (DM) is the only screening modality that has been proven to reduce mortality from breast cancer through early detection. However, to reduce false positive results and improve the sensitivity of DM, we undertook a study to compare the impact of digital breast tomosynthesis (DBT) to DM in the evaluation of symptomatic women using the breast imaging reporting and data system (BIRADS) score.
Aims and Objectives: The aim of the study was to compare the impact of DBT to DM in the evaluation of symptomatic women using BIRADS score.
Materials and Methods: This cross-sectional study of 100 symptomatic patients in the age group of 35–85 years who underwent DM and DBT was included in the study and was analyzed using the American College of Radiology-BIRADS score. Patients with a palpable breast lump, pain, nipple discharge, skin dimpling, or skin changes over breast and nipple inversion or other nipple abnormalities were included in the study.
Results: Comparison based on the diagnostic accuracy of mammography alone and mammography plus DBT based on BIRADS score revealed DM had a sensitivity of 96%, specificity of 40.6%, a positive predictive value (PPV) of 72.9% and negative predictive value (NPV) of 86.7% with an accuracy of 75.3% while DM plus DBT had a sensitivity of 98.1%, specificity of 46.9%, the PPV of 75.4%, and NPV of 78.8%. There was no significant increase in sensitivity (P=1.000), specificity (P=0.614), PPV (0.734), and accuracy (0.584).
Conclusion: DM plus DBT does not change the BIRADS scoring but its addition increases the diagnostic confidence while there is no significant increase in sensitivity/specificity/PPV/NPV or diagnostic accuracy using DM plus DBT.
Chronic and acute non-healing wounds represent a major public health problem, and replacement of cutaneous lesions by the newly regenerated skin is challenging. Platelet-rich plasma (PRP) is a widely used throughout diverse fields of medicine for improving tissue regeneration. The aim of this study was to evaluate the effectiveness of autologous platelet-rich plasma (PRP) in individuals with chronic and acute non-healing wounds. This prospective study was carried out in the Department of Orthopaedics, Rajawadi Muncipal General Hospital, Mumbai in which a total of 13 patients were enrolled.
Introduction: There is no unanimous opinion for the use of grafting agent in the reconstruction of depressed tibial condyle fracture. Autograft is most commonly used filling agent for elvation of depressed tibial condyle fracture. However there are certain limitations which led to a recent attraction toward synthetic bone substitute like crystalline hydroxyl apatite granules and blocks. In this study, we have compared the functional outcome and complications of autograft and bone graft substitute in reconstruction of depressed tibial condyle fractures. Materials and Methods: A total of 40 patients with acute tibial condyle fracture were studied. Bone graft substitute and autograft were applied in 20 and 20 cases, respectively. The age of the patients was between 20 to 50 years, and the minimum followup period of patients was 12 months and maximum was 18 months .The Radiological and functional assessment was done using the modified Rasmussen clinical criteria. Results: A total of two infections were observed, which occurred in patients with Bone graft substitute. Articular surface collapse was seen in three patients, with two bone graft substitute and one autograft patients. The mean clinical score was 18.50 and 18.55 in autograft and allograft received patients, respectively (p = 0.09). The mean radiological score was 15.50 and 15.60 in autograft and bone graft substitute received patients (p = 0.3). In bone graft substitute there was no graft doner site morbity. Conclusion: While comparing the complication rate, functional and radiological outcome of bone graft substitute versus Autograft reconstruction of TPF, hydroxy apatite allograft could be used as a good alternative of autograft as well.
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