A861ing (MRI). Methods: A prospective intensive monitoring study was carried out in department of radiodiagonsis and imaging, Kasturba Hospital Manipal. The Institutional Ethics Committee (IEC 411/2013) approved this study. Patients meeting the study criteria were considered for the enrollment in the study. Those patients who receives radiocontrast media intravenously in the diagnostic procedure, intensively monitored for occurrence of ADRs during their hospital stay. Patient interview also performed to get details about ADRs. Results were analyzed using descriptive analysis and Pearson's Chi-square test to determine the relationship between the ADRs and the factors. Reported ADRs analyzed for patients demographics characteristics, WHO and Naranjo's causality, severity, predictability, preventability. Results: Total of 485 patients were enrolled in the study, 62 patients developed 75 ADRs. The overall incidences of ADRs were 12.8%. Acute reactions were found to be in 15 patients, delayed reactions in 46 patients, Asthma was found to be increasing the risk of developing ADR. Most of the ADRs are under mild (72%) category, moderate and severe reactions were found to be 24% and 4% respectively. Most frequently reported organ system were found to be gastrointestinal (25.3%), skin and appendage ( 18.6%) and Body as whole general disorder (37.3%). Overall incidence of ADR from MRI contrast media was found to be 3.4%.Total of 116 patients enrolled in this study. Female and neoplasm patients had higher incidence of ADRs. High incidence found in younger people (25 to 44 years). All the ADRs were under mild category. Most of the ADRs were found to be associated with Gastro-intestinal system and Body as whole general disorders. ConClusions: Incidence of adverse drug reaction from radio contrast media were found to be less but special care should be given for high risk patients.
Objective The purpose of this article is to investigate the analgesic effect of flurbiprofen ester injection continuous intravenous drip in transvaginal 4-dimensional hysterosalpingography (TVS 4D-HyCoSy). Methods Two hundred thirty patients who underwent TVS 4D-HyCoSy for infertility from May 2018 to August 2021 at Sun Yat-sen Memorial Hospital, Sun Yat-sen University, were selected. They were grouped according to tubal patency, flurbiprofen ester use, and uterine cannula diameter, i.e., bilateral tubal patency group and nonbilateral tubal patency group, atropine group and atropine + flurbiprofen ester group, and coarse tube group and fine tube group, to compare the analgesic effect during TVS 4D-HyCoSy, pain relief effect between groups, record the incidence of adverse effects, and analyze the factors related to the influence of pain. Results 1. The atropine + flurbiprofen ester group had significantly fewer adverse effects in the former patients compared with the atropine group; 2. Flurbiprofen ester continuous intravenous infusion was effective for analgesia after ultrasound tubal contrast. Flurbiprofen ester continuous intravenous infusion was effective in relieving pain within 30 minutes after imaging regardless of the patency of the fallopian tubes; 3. The addition of flurbiprofen ester significantly relieved pain in the fine tube group in those with bilateral patency of the fallopian tubes and in the thick tube group and fine tube group in those with nonbilateral patency of the fallopian tubes; 4. Multifactorial analysis of pain relief during imaging suggested that the use of flurbiprofen for bilateral tubal patency had a significant positive effect on pain relief within 30 minutes after the examination, AUC 0.732; 95% CI: 0.665-0.798. Conclusion Bilateral tubal patency and flurbiprofen will have a significant positive effect on pain relief. The analgesic effect of flurbiprofen ester injection with continuous drip started before TVS 4D-HyCoSy was good, and the pain relief effect was significant within 30 minutes after examination with few adverse effects, which is worthy of clinical promotion.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.