Background: Giant solitary schwannomas are rare, benign, and typically slow-growing tumors reaching up to 20 cm in size. Case Description: A 43-year-old male presented with shortness of breath and chest pain. The thoracic MRI showed a giant mass 15 cm in diameter filling the left chest cavity. The lesion was resected utilizing intrathoracic approach and required a multilevel approach. Vertebrectomy with instrumented fusion was performed. The pathological diagnosis was benign schwannoma without nuclear atypia. Postoperatively, the patient fully recovered without sequelae. Conclusion: A 43-year-old male presented with a 15 cm diameter chest mass that proved to be a schwannoma that was resected without long-term sequelae.
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