Backgroud : Insulin resistance is a pathogenic hallmark of type 2 diabetes mellitus (T2DM).Serum ferritin, a predominant iron-storage protein and a biomarker of iron stores, are elevated in persons with prevalent diabetes as compared with non-diabetic controls and correlate with impaired fasting glucose levels.High ferritin levels have been associated with the metabolic syndrome and measures of insulin resistance .The aim of the current study : is to measure Serum Ferritin in patients with type 2 diabetes in Beni-Suef governorate and to study the relationship between serum Ferritin and Insulin Resistance. Patients and Methods : This study involved 40 patients with type 2 diabetes (24 females and 16 males) and 20 healthy adults (12 females and 8 males) served as a control group. All groups included in this study were subjected to Full History Taking, Clinical Examination including (BMI & Waist Circ.) and Laboratory Investigation including ( FPG, HbA1c, Serum Ferritin and Fasting Serum Insulin & measuring HOMA-IR).Results : Ferritin showed a statistically significant correlation with Waist Circ., FPG, HbA1c, Fasting Serum Insulin and Insulin Resistance (HOMA-IR) in the diabetic group (P < 0.05) .Conclusion: Serum ferritin can be used as a marker of insulin resistance syndrome in diabetics
Helicobacter pylori is a microaerophile Gram-negative bacillus, resistant to the activity of gastric juice. The bacteria may take the vegetative form (spiral shape) or sporulation form .Liver cirrhosis and H.Pylori infection are two common diseases in our population and reducing the incidence of complications in cirrhotic subjects is an important step in current gastroenterology practice. The aim of the present study is to determine incidence of H. Pylori infection among patients with liver cirrhosis secondary to HCV infection and study the correlation between esophageal varices degree and H. Pylori infection. This study involved 50 patients with liver cirrhosis secondary to Hepatitis C Virus infection were selected from gastroenterology and internal medicine clinics at Beni-Suef general hospital and Beni-Suef university hospital. Our results illustrate that the percent of H. pylori infection among studied patients was 68%, our results illustrate that there is statistically significant association between the grade of varices and the detection of H. pylori; p value is less than 0.001.
The goal of this systematic review was to to assess outcomes in individuals with AAFD (focusing on stage II). Three databases were searched for terms referring to the PTTD and AAFD up to and including 31 July 2018. Studies were eligible if they were published in English language and contained data on outcomes of stage II Management. Thirty-two eligible studies were included in this review. The sample size of the treatment trials ranged from 12 to 129 patients, with only two trials having more than 100 participants. The age ranges were wide. Pain, adverse effects, function or disability indices of foot, patients' satisfaction, radiographic parameters, alignment and improvement of foot function, and quality of life were the searched outcomes. Due to clinical and methodological heterogeneity, data were not pooled into meta-analysis. The evidence from the selected studies is currently too limited about each procedure compared to its counterpart to draw definitive conclusions about the use of each intervention for AAFD. Future high quality comparative studies are warranted in this field. Only limited interventions commonly used in practice have been studied and there is much debate over the treatment of symptomatic and asymptomatic adult pes planus.
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