Objective : Hyperostosis in meningiomas can be present in 4.5% to 44% of cases. Radical resection should include aggressive removal of invaded bone. It is not clear however to what extent bone removal should be carried to achieve pathologically free margins, especially that in many cases, there is a T2 hyperintense signal that extends beyond the hyperostotic bone. In this study we try to investigate the perimeter of tumour cells outside the visible nidus of hyperostotic bone and to what extent they are present outside this nidus. This would serve as an initial step for setting guidelines on dealing with hyperostosis in meningioma surgery. Methods : This is a prospective case series that included 14 patients with convexity meningiomas and hyperostosis during the period from March 2017 to August 2018 in two university hospitals. Patients demographics, clinical, imaging characteristics, intraoperative and postoperative data were collected and analysed. In all cases, all visible abnormal bone was excised bearing in mind to also include the hyperintense diploe in magnetic resonance imaging (MRI) T2 weighted images after careful preoperative assessment. To examine bony tumour invasion, five marked bone biopsies were taken from the craniotomy flap for histopathological examinations. These include one from the centre of hyperostotic nidus and the other four from the corners at a 2-cm distance from the margin of the nidus. Results : Our study included five males (35.7%) and nine females (64.3%) with a mean age of 43.75 years (33-55). Tumor site was parietal in seven cases (50%), fronto-parietal in three cases (21.4%), parieto-occipital in two cases (14.2%), frontal region in one case and bicoronal (midline) in one case. Tumour pathology revealed a World Health Organization (WHO) grade I in seven cases (50%), atypical meningioma (WHO II) in five cases (35.7%) and anaplastic meningioma (WHO III) in two cases (14.2%). In all grade I and II meningiomas, bone biopsies harvested from the nidus revealed infiltration with tumour cells while all other bone biopsies from the four corners (2 cm from nidus) were free. In cases of anaplastic meningiomas, all five biopsies were positive for tumour cells. Conclusion : Removal of the gross epicentre of hyperostotic bone with the surrounding 2 cm is adequate to ensure radical excision and free bone margins in grade I and II meningiomas. Hyperintense signal change in MRI T2 weighted images, even beyond visible hypersototic areas, doesn't necessarily represent tumour invasion.
Cavernous haemangioma of the cavernous sinus is a rare vascular malformation. It's often confused with other parasellar masses. Here, we report a case of a female with a left parasellar mass which was misdiagnosed as schwannoma vs meningioma using CT and MRI. The patient was operated via the pterional approach but resection had been halted due to severe haemorrhage and only tumour biopsy could be obtained. The diagnosis of cavernous sinus haemangioma was established by histopathology and confirmed by subsequent digital subtraction angiography. The patient refused second surgery or adjuvant radiosurgery and the treatment strategy was observation and follow-up. Retrospectively, we included the key radiographic features of cavernous sinus haemangioma which would facilitate pre-operative diagnosis and avoid unforeseen operative complications. Diagnostic radiographic features include a well-defined mass in the cavernous sinus which shows isodense to slightly hyperdense attenuation on non-contrast CT scan with possible adjacent pressure bone remodelling. On MRI, it shows remarkable high T2 signal; intense homogenous enhancement or characteristic progressive contrast enhancement on sequential enhanced images. On digital subtraction angiography, it may demonstrate a vascular blush.
Introduction Traumatic odontoid fracture type 2 is not uncommon in cervical spine trauma. Different techniques of fusion are usually applied depending on many factors with the aim of acquiring bony fusion at C1–2 segment. Material and Methods Twenty patient of traumatic type 2 odontoid fractures were operated in our institute from December 2010 till march 2014. Sublaminar wiring was done in 10 cases and the rest were operated by C1–2 screw fixation. Clinical condition and bony fusion were evaluated at 3 and 6 months. Results Fourteen patients were with improving or stationary clinical state plus good fusion signs. While six patients developed either clinical deterioration or radiological failure of fusion. Among these six patients, four cases were fused by sublaminar wire and two patients were operated by screw and rod fixation. All cases with fusion failure were re operated again. Conclusion Screw system fixation for traumatic odontoid fracture type 2 take upper hand than sublaminar wiring regarding bony fusion and clinical condition but longer time follow-up and larger series are needed.
Introduction Dorsal lesions localization has been always challenging with high incidence of missed level. Although development of diagnostic tools but it is not always available in many centers. Patients and Methods During the period from December 2010 to June 2013, 14 cases with dorsal intraspinal lesions were operated with preoperative localization using dye injection in the assigned laminae over the lesion. CT dorsal spine done preoperative and fluoresce was injected into the proper level lamina. Results In the 14 patients, it was easy to localize the target lamina by the color of the dye and in 13 patients it was over the lesion. There was no side effect from injecting dye locally in spine. The use of intraoperative fluoroscope was obviously limited. Conclusion Preoperative laminar dye injection is safe and effective technique in dorsal spine leveling especially in limited resource centers. Although it is little invasive but its results are much better than surface metallic localizers.
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